melanophage


Also found in: Encyclopedia.

melanophage

 [mel´ah-no-fāj″]
a histiocyte laden with phagocytosed melanin.

mel·a·no·phage

(mel'ă-nō-fāj'),
A histiocyte that has phagocytized melanin.
[melano- + G. phagein, to eat]

melanophage

(mĕl′ə-nə-fāj′, mə-lăn′ə-)
n.
A macrophage that has taken in melanin by phagocytosis.

mel·a·no·phage

(mel'ă-nō-fāj)
A histiocyte that has phagocytized melanin.
[melano- + G. phagein, to eat]
References in periodicals archive ?
Histopathology of this pigmented lesion showed acanthotic epidermis with melanin pigmentation of basal keratinocytes and papillary dermal nodular accumulation of melanophages and lymphocytes, which were consistent with tumoral melanosis.
Dermoscopy of the lesion typically shows gray-blue to bluish small dots over a bluish background, corresponding to melanin-laden melanophages in deeper dermis (Tyndall effect), as is illustrated in the present case [12].
The vessels in the papillary dermis may be dilated and associated with inflammatory infiltrate.(1011) PBD shows the presence of increased melanin in basal layer and melanophages in the dermis.
In LP-like GVHD, focal increases in the granular cell layer and vacuolar changes of basal layer often reveal in the epidermis, and melanophages and a large number of lymphocytic infiltrate are common showing in the dermis.
Few inflammatory cells and melanophages can be observed in the dermis [53, 58].
Histopathology shows increased melanin and a normal or slightly increased number of melanocytes in the basal layer of the epidermis and increased pigmentation within macrophages (melanophages) in the papillary dermis [41].
Most cases of MS are benign though 10% of them are malignant with metastasis that is characterized by epithelioid cells with variably sized nuclei and marked accumulation of melanin in neoplastic cells and melanophages [2, 5].
Horster et al., "Alterations in the epidermal-dermal melanin axis and factor XIIIa melanophages in senile lentigo and ageing skin," British Journal of Dermatology, vol.
A biopsy may show signs of post-inflammatory infiltrate of the papillary dermis with dermal melanophages. (4,5)
Rarely, small assemblies of dark pigmented cells (melanophages) were found in the separating connective tissue septa.
Hyperkeratosis, acanthosis and melanophages stained in brown-black colour are seen (crystal violetx400).
LP lesion may resolve with residual hyperpigmentation caused by a persistent increase in the number of melanophages in the papillary dermis [96,100].