melanoma in situ

melanoma in situ

A melanoma characterised by pagetoid spread of atypical cells or nests along the epidermal junction, extending up into the epidermis, but not the dermis. The cells are hyperchromatic, angulated and large. Mitoses may be seen.

DiffDx
Shave biopsied intradermal naevus.

mel·a·no·ma in si·tu

(mel'a-nō'mă in sī'tū)
A melanoma limited to the epidermis and composed of nests of atypical melanocytes and scattered single cells extending into the upper epidermis; local excision is curative although the lesion, if untreated, may soon invade the dermis. Malignant lentigo may be considered a slowly progressive type of melanoma in situ.
References in periodicals archive ?
With a one in 50 lifetime risk of developing melanoma, nearly 74,000 Americans are expected to be diagnosed with Stage I-IV melanoma and another 63,000 will be diagnosed with melanoma in situ -- totaling nearly 137,000 total diagnoses.
Tannous ZS, Lerner LH, Duncan LM, Mihm MC Jr, Flotte TJ: Progression to invasive melanoma from malignant melanoma in situ, lentigo maligna type.
In his practice, he uses imiquimod for patients with all types of BCC, for those with in situ and superficially invasive squamous cell carcinoma (SCC), and for those with melanoma in situ.
The second is divided into 4 levels depending on the characteristics of diffusion and metastasis of melanomas, first class includes melanoma in situ, second class radial growth melanoma, third class vertical growing melanomas that have acquired skills to penetrate surrounding tissues.
A 41-year-old man had a superficial spreading melanoma in situ, Clark's level I, removed from his anterior abdominal wall.
The term melanoma in situ is used when the basement membrane of the epidermis is not penetrated by the melanocytes (about 50,000 such cases occur yearly in the U.
With a one in 50 lifetime risk of developing melanoma, nearly 74,000 Americans are expected to be diagnosed with diagnosed with Stage I-IV melanoma and another 63,000 will be diagnosed with melanoma in situ -- totaling nearly 137,000 total diagnoses.
Rosen L, Amazon K, Frank B: Bowen's disease, Paget's disease and malignant melanoma in situ.
This was a melanoma in situ without an inflammatory infiltrate, so there was no confusion about the lesion's true depth.
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