melanocyte


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melanocyte

 [mel´ah-no-sīt″, mĕ-lan´o-sīt]
any of the dendritic clear cells of the epidermis that synthesize tyrosinase and, within their melanosomes, the pigment melanin; the melanosomes are then transferred from melanocytes to keratinocytes. adj., adj melanocyt´ic.

mel·a·no·cyte

(mel'ă-nō-sīt),
A pigment-producing cell located in the basal layer of the epidermis with branching processes by means of which melanosomes are transferred to epidermal cells, resulting in pigmentation of the epidermis. It is also present in the basal layer of the epithelium of the oral cavity.
[melano- + G. kytos, cell]

melanocyte

(mĕl′ə-nō-sīt′)
n.
An epidermal cell capable of synthesizing melanin.

melanocyte

A specialised cell found at the dermal-epidermal junction—as well as the uvea, inner ear and meninges—which produces and stores melanin.

mel·a·no·cyte

(mel'ă-nō-sīt)
A pigment-producing cell located in the basal layer of the epidermis with branching processes by means of which melanosomes are transferred to epidermal cells, resulting in pigmentation of the epidermis.
[melano- + G. kytos, cell]

melanocyte

A pigment cell of the skin. A cell carrying MELANIN or capable of producing melanin.

melanophore

or

melanocyte

a type of pigment cell (or CHROMATOPHORE) that contains the pigment melanin, usually found in the skin of animals. It has a protective or camouflage function.

melanocyte

A pigment-bearing cell. It is found in the iris, the choroid, the retina, the sclera, the skin, etc. See melanin; choroidal naevus; iris naevus.
References in periodicals archive ?
Citation: Chieko Hosaka et al., Induced pluripotent stem cell-derived melanocyte precursor cells undergoing differentiation into melanocytes.
A team of scientists in France are working to try and stop the melanocytes from being damaged at the end of each hair cycle.
Dominant white (I) pigs lack mature melanocytes in the skin as well as lacking precursor melanocytes as would be anticipated for a KIT mutation (Johansson-Moller et al., 1996).
Lemmer, "Melanocyte biology and function with reference to oral melanin hyperpigmentation in HIV-seropositive subjects," AIDS Research and Human Retroviruses, vol.
Garcia-Borron, "Inhibition of melanogenesis in response to oxidative stress: transient down-regulation of melanocyte differentiation markers and possible involvement of microphthalmia transcription factor," Journal of Cell Science, vol.
Chou et al., "Coordinated activation of wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration," Cell, vol.
They found that control of these cells, known as melanocyte stem cells, is regulated by two key signalling pathways - part of the endothelin receptor type B (EdnrB) and Wnt signalling pathways.
Therefore, there is an urgent need to find new strategies to expand our knowledge of melanomagenesis.We propose a new approach to unravel the complexity of melanoma: To use a cellular differentiation model to decipher the role of epigenetic regulation during melanocyte differentiation and its contribution to melanoma progression.
ROS oxidize components of cells, leading to melanocyte destruction and creating depigmented macules [8].

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