MC3R

(redirected from melanocortin 3 receptor)

MC3R

A gene on chromosome 20q13.2-q13.3 that encodes a receptor for alpha, beta and gamma melanocyte stimulating hormone (MSH), the activity of which is mediated by G protein-activated adenylate cyclase. MC3R is expressed in tissues other than the adrenal cortex and melanocytes.

Molecular pathology
MC3R mutations are associated with susceptibility to obesity.
References in periodicals archive ?
Melanocortin 3 receptor gene and melanocortin 4 receptor gene mutations: the Asian Perspective.
Melanocortin 3 receptor (MC3R) gene variants in extremely obese women.
Melanocortin 3 receptors control crystal-induced inflammation.