TPO is a liver-produced protein that regulates megakaryocytopoiesis
and plays a role in the increase in platelet counts.
in experimental iron deficiency anemia.
Pennucci et al., "miR-494-3p overexpression promotes megakaryocytopoiesis
in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6," Oncotarget, vol.
Spencer et al., "Stimulation of megakaryocytopoiesis
and thrombopoiesis by the c-Mpl ligand," Nature, vol.
Extramedullary hematopoiesis (mainly erythropoiesis and megakaryocytopoiesis
) and erythrophagocytosis were reported by other authors (FIGHERA et al., 2010; DA SILVA et al., 2011).
Muszbek, "Factor XIII: A marker of mono- and megakaryocytopoiesis
," British Journal of Haematology, vol.
Clinical and cytogenetic correlations of abnormal megakaryocytopoiesis
in patients with acute leukemia and chronic myelogenous leukemia in blasts crisis.
New insights into the thrombopoietic status of patients on dialysis through the evaluation of megakaryocytopoiesis
in bone marrow and of endogenous thrombopoietin levels.
Thrombopoietin (TPO), also known as Megakaryocyte Growth and Development Factor (MGDF) or c-MpL ligand, is a hormone which is synthesized in the liver and dominantly regulates the process of megakaryocytopoiesis
Palumbo et al., "MicroRNA fingerprints during human megakaryocytopoiesis
," Proceedings of the National Academy of Sciences of the United States of America, vol.
Stimulation of megakaryocytopoiesis
in mice by human modified C-reactive protein (mCRP).