mefloquine


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mefloquine

 [mef´lo-kwin]
an antimalarial agent effective against chloroquine-resistant strains of Plasmodium falciparum and P. vivax; used as the hydrochloride salt.

mefloquine

/mef·lo·quine/ (mef´lo-kwin) an antimalarial effective against chloroquine-resistant strains of Plasmodium falciparum and P. vivax; used as the hydrochloride salt.

mefloquine

(mĕf′lə-kwīn′, -kwēn′)
n.
A drug, C17H16F6N2O, used in its hydrochloride form for the treatment and prevention of chloroquine-resistant malaria.

mefloquine

[mef′ləkēn]
an antimalarial for the prophylaxis and treatment of malaria caused by chloroquine-resistant strains of Plasmodium falciparum, or P. vivax.

mefloquine

The prophylactic agent of choice for preventing malaria in those travelling to areas with drug-resistant Plasmodium falciparum.
 
Adverse effects
GI tract disturbances, dizziness; at high doses, convulsions, hallucinations.

mefloquine

A drug used to prevent and treat MALARIA. The drug is effective but has been criticized for its neuropsychological side effects which include fatigue, depression, headache, insomnia and distressing dreams. The drug is on the WHO official list. A brand name is Lariam.

Mefloquine

An antimalarial drug that was developed by the United States Army in the early 1980s. Today, malaria resistance to this drug has become a problem in some parts of Asia (especially Thailand and Cambodia).
An antimalarial drug that was developed by the United States Army in the early 1980s. Today, malaria resistance to this drug has become a problem in some parts of Asia (especially Thailand and Cambodia).
Mentioned in: Malaria
References in periodicals archive ?
Decreasingpfmdr1 copy number in Plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
At the beginning of the project, it was decided that only one single supplier of mefloquine would be chosen, with an industrial production route that was very dependent on the characteristics of the API.
It is plausible that the patient's age may also affect the concentration of mefloquine in the blood components.
Documents recently acquired by Nevin indicate that Bales may have been taking mefloquine before the murders.
One of the new compounds, when combined with mefloquine, killed off all of the parasites in some mice with just a single oral dose and allowed those mice to live almost twice as long as those treated with conventional ACT.
A BOXED WARNING ABOUT POTENTIAL PSYCHIATRIC and nerve effects has been added to the label for the antimalarial agent mefloquine hydrochloride.
With failure rates ranging between 50 to 95% reported for chloroquine in parts of Nigeria (Falade et al, 2005; FMOH, 2004) and resistance to the classical antimalarial drugs, notably--chloroquine, sulfadoxine-pyrimethamine, mefloquine, quinine been well documented (White, 1992; Krogstad, 1996).
Two of the most common agents--chloroquine and mefloquine -are no longer effective in many parts of Mexico, Central and South America, the Middle East, sub-Saharan Africa, India, and Southeast Asia.
Among the perspectives covered are from breathing bad air to biting beasts, anti-microbials to anti-malarials, quinine to mefloquine, qinghausu as the sweet wormwood of success, possible control by blocking transmission, and the dream of eradication.