Among patients with a medication possession ratio
less than 50%, 13.4% were hospitalized for ischemic heart disease or ischemic stroke, compared with 11.5% of patients who had a medication possession ratio
of 90% or above, even after adjustment for baseline characteristics.
Adherence (median Medication Possession Ratio
) according to OAB medication, age category and treatment status (the reference comparator is shown as a black column in each case).
Wong and his associates calculated a medication possession ratio
based on the frequency at which a patient's records documented receiving an injection, and the number of days the injection covered during follow-up.
ADAP, AIDS Drug Assistance Program; IVDU, intravenous drug users; MPR, medication possession ratio
; MSM, men who have sex with men; RWCA, Ryan White catchment area.
Researchers have developed the medication possession ratio
(MPR), which is often defined as the number of days of medication dispensed as a percentage of time, such as 365 days.
In addition, enrollees with gaps in their purchases of chronic medication, identified through claims data as < 60 percent adherent over the past 270-day period measure by medication possession ratio
(MPR) (Fairman and Motheral 2000) were mailed an educational message that highlighted the importance of medication adherence.
The investigators measured adherence using a metric called the medication possession ratio
(MPR), defined as the amount of medication filled divided by the amount needed to fill to take as prescribed.
Interestingly, during the one-year follow-up period, the adherence behavior (as measured by the medication possession ratio
) of the patients treated with depot formulations improved.
The study confirmed that patients need to achieve a medication possession ratio
(MPR) of at least 80% (meaning that they are adherent to 80% or more of their prescription medications) in order to reduce their risk of hospital readmission after a heart attack.
The children's mean medication possession ratio
, a measure of adherence, was 0.54.
The model included age, gender, employee (versus spouse), pre-period medication continuation as measured by the medication possession ratio
(MPR, i.e., the number of unique days that one or more medications in the class was available to the patient in the year before three-tier adoption divided by 360), the proportion of prescriptions filled through the mail-order program in the year before adoption, median household income for the zip code of residence, and a risk index.
Patients who received automated IVR telephone reminders had a significantly higher medication possession ratio
compared with patients who did not receive reminders.