Oxidative stress mediates air pollution particle-induced acute lung injury and molecular pathology.
The UP-induced constriction of rat pulmonary artery was also attenuated by PD98059 and SB203580 (Figure 3C,D), indicating that activation of ERK1/2 and p38 may mediate UP-induced pulmonary vasoconstriction.
bacterial-bacterial interactions in a human intestinal organ culture model (3).
Membrane-initiated steroid actions and the proteins that mediate
These data suggest that the ERK-2 pathway is a senstitive biomarker to detect environmental stress and that the ERK pathway mediates
cell death in response to [H.sub.2][O.sub.2] and LPS.
Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates
transactivation, enhancer-promoter communication, and changes in chromatin structure.
Molecular basis of nonresponsiveness to peroxisome proliferators: the guinea-pig PPARalpha is functional and mediates
peroxisome proliferator-induced hypolipidaemia.
The role for a P2X7 receptor in [GH.sub.4][C.sub.1] cells has not been determined; however, it is well known that this cell lineage (growth hormone-producing cells) mediates
local inflammatory responses in the pituitary gland and may modulate the hypothalamic pituitary axis during systemic inflammatory reactions (30).
GR, a member of the nuclear receptor superfamily, mediates
glucose homeostasis, immune modulation, cellular growth and differentiation, and numerous other physiological responses in a wide variety of tissues (33-36).
Furthermore, the mediator who is the hinge in this triadic relationship, acts not only on their own behalf, though they invariably have some interest, but on behalf of the people between whom they mediate
. This triadic relationship involves the double transmission of information, values and messages between the client and mediator, and mediator and someone else.
Glucose transporters GLUT 1 and GLUT 3 mediate
transport of DHA (Vera et al.