It is most commonly associated with radiation therapy for lung cancer, and less frequently with other tumors such as breast cancer and mediastinal lymphoma, respectively in about 5-50%, 5-10%, and 1-5% of the cases (1,2).
Evolution of radiation techniques in the treatment of mediastinal lymphoma: from 3D conformal radiotherapy (3DCRT) to intensity-modulated RT (IMRT) using helical tomotherapy (HT): a single-centre experience and review of the literature.
However, post therapy persistence of mediastinal tumor and disappearance of all heart masses could stand for mediastinal lymphoma
with secondary cardiac infiltration.
The average age of a patient with mediastinal lymphoma
is 30 years.
There remain cases of mediastinal lymphoma
of B-cell lineage that cannot be definitively classified despite extensive phenotypic and molecular studies.
When the disease affects all of a cat's lymph nodes, it is termed "multicentric." The other major types include mediastinal lymphoma
, which affects the thymus gland or lymph nodes in the center of the chest cavity; gastrointestinal lymphoma, which affects the alimentary tract; cutaneous lymphoma, which affects the skin; and leukemia, which originates in the bone marrow.
Draisma et al compared the utility of gallium and MRI scans for detecting mediastinal lymphoma
in 189 patients.
Primary mediastinal lymphomas
usually occur in anterior mediastinum and account for 20% of neoplasms in adults and about 50% in paediatric age group [3,8,15] which correlates with the present study.
Diagnosis and subtyping of de novo and relapsed mediastinal lymphomas
by endobronchial ultrasound needle aspiration.
Among the mediastinal lymphomas
, Hodgkin Lymphoma (HL) exclusively including Nodular Sclerosis HL (NSHL) constituted about 58.33% cases, whereas Non-Hodgkin Lymphoma (NHL) accounted to only about 44.67% cases (Table 2) including Precursor T-cell Lymphoblastic lymphoma (pre-T LBL) and diffuse large B-cell lymphoma (DLBCL).