mediastinal lipomatosis

me·di·as·ti·nal lip·o·ma·to·sis

increased mediastinal fat caused by taking steroids.
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Imaging alone was the modality of investigation which confirmed cases like mature teratoma, aneurysm of ascending aorta and mediastinal lipomatosis; 9 of 30 cases were NHL, 8 of them located in anterior mediastinum.
No further investigations were done in 5 cases (Mediastinal lipomatosis, intrathoracic aneurysm of aorta and 3 cases of teratoma) since CT alone was sufficient in the diagnosis.
Case Number (%) 1 Non-Hodgkin's Lymphoma 9(30%) 2 Lung Cancer 4(13.3%) 3 Thymoma 4(13.3%) 4 Teratoma 3(10%) 5 Retrosternal Thyroid Carcinoma 1(3.3%) 6 Mediastinal Lipomatosis 1(3.3%) 7 Synovial Sarcoma 1(3.3%) 8 Intrathoracic Aneurysm 1(3.3%) 9 Metastasis 1(3.3%) 10 Bronchogenic Cyst 2(6.6%) 11 Unknown Aetiology 1(3.3%) 12 Neurofibroma 2(6.6%) Fig.
Mediastinal lipomatosis (ML) is a rare condition caused by excessive fat accumulation in the mediastinum (1).
Mediastinal lipomatosis is a rare complication of systemic steroids and was described by Koerner and Sun (1) in 1966 for the first time.
The diagnosis of mediastinal lipomatosis is generally made by observation of mediastinal enlargement on chest graphy and demonstration of intensity changes related to fat on CT or MR imaging.
Mediastinal lipomatosis secondary to steroid therapy.
(2.) Nguyen KQ, Hoeffel C, Le LH, Phan HT Mediastinal lipomatosis. South Med J 1998; 91: 1169-1172.
Mediastinal lipomatosis: a complication of high dose steroid therapy in children.
Anesthetic considerations in steroid-induced mediastinal lipomatosis. Anesth Analg 2004; 98: 862-864.
In one of our patient mediastinal widening was interpreted as mediastinal lipomatosis and later after bilateral adrenalectomy, he presented with inoperable thymic carcinoid.
Cushing's syndrome with mediastinal lipomatosis. Clinical Note.
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