meconium plug syndrome
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meconium ileusA condition characterised by obstruction of the neonatal intestine by meconium that may be confined to the ileus, a finding characteristic of cystic fibrosis.
Non-passage of stool in the first two days of life, vomiting, abdominal distension.
Volvulus, intestinal infarction.
Meconium “plugging” of the rectum may also signal the presence of Hirschsprung’s disease, which is histologically characterised by segmental aganglionosis.