meconium plug syndrome


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meconium ileus

A condition characterised by obstruction of the neonatal intestine by meconium that may be confined to the ileus, a finding characteristic of cystic fibrosis.
 
Clinical findings
Non-passage of stool in the first two days of life, vomiting, abdominal distension.

Complications
Volvulus, intestinal infarction.
 
DiffDx
Meconium “plugging” of the rectum may also signal the presence of Hirschsprung’s disease, which is histologically characterised by segmental aganglionosis.
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References in periodicals archive ?
For the Lesions in the large intestine, hypoplastic left colon syndrome, ano-rectal malformation, intestinal neuronal dysplasia and Meconium plug syndrome are the differentials.
Meconium plug syndrome is a diagnosis of exclusion but is the mildest and most common cause of bowel obstruction in the newborn.