meconium aspiration syndrome


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Related to meconium aspiration syndrome: respiratory distress syndrome

fe·tal as·pi·ra·tion syn·drome

a syndrome resulting from uterine aspiration of amniotic fluid and meconium by the fetus, usually caused by hypoxia and often leading to aspiration pneumonia.

meconium aspiration syndrome

The in utero passage of meconium, which occurs mainly in mature or postmature infants and often associated with foetal distress or anoxia.

Risk factors
Difficult delivery; foetal distress; intrauterine and/or peripartum hypoxia (due to cerebral haemorrhage, vagal reflex, intrauterine pneumonia, congenital heart disease, other malformation, or drugs), which triggers increased GI peristalsis and relaxation of anal sphincter, resulting in passage of meconium into the amniotic fluid. If the infant makes breathing movements in utero, meconium-rich amniotic fluid can flow into the lungs, causing a partial or complete blockage of the airways, resulting in post-natal dyspnoea, poor gas exchange, airway inflammation and pneumonia. Meconium staining of the amniotic fluid with possible aspiration occurs in 5–10% of births. About one third of the infants with meconium aspiration require some type of assisted breathing. It is a leading cause of death in neonates.

Clinical findings
Low APGAR scores; tachypnoea, dyspnoea and cyanosis, which either resolves in the first three days of life, or if aspirated meconium was significant, patchy infiltrates on chest films, with atelectasis, emphysema and rales.

Management
Extracorporeal membrane oxygenation.

meconium aspiration syndrome

Neonatology A symptom complex caused by the aspiration of meconium at the time of delivery, especially if post-term Clinical Low Apgar scores, tachypnea, dyspnea, cyanosis, which either resolves in the first 3 days of life, or if aspirated meconium was significant, patchy infiltrates on CXR, with atelectasis, emphysema, rales Risk factors Post-term, difficult delivery, fetal distress, intrauterine and/or peripartum hypoxia, triggering increased GI peristalsis. Cf Apgar.

fe·tal as·pi·ra·tion syn·drome

(fē'tăl as'pir-ā'shŭn sin'drōm)
A manifestation resulting from aspiration of amnionic fluid and meconium by the fetus, usually caused by hypoxia and often leading to aspiration pneumonia.
Synonym(s): meconium aspiration syndrome.

meconium aspiration syndrome

A disorder resulting from the passage of meconium by the fetus into the amniotic fluid followed by the diffusion or inspiration of meconium into the fetal airways. Meconium staining of amniotic fluid occurs in about 12 percent of pregnancies and the syndrome affects about 5 percent of these. The death rate from respiratory complications is about 4 percent of affected fetuses and survivors may have pulmonary hypertension or asthma. Surfactant function is compromised.

Meconium aspiration syndrome

Breathing in of meconium (a newborn's first stool) by a fetus or newborn, which can block air passages and interfere with lung expansion.
References in periodicals archive ?
Only two pre term infants were observed with meconium aspiration syndrome. Although, the incidence of meconium aspiration syndrome is less in premature, but because of small sample size in our cohort, its exact relationship with the gestational age needs larger survey.
TABLE 1: SHOWING VARIOUS MATERNO-FETAL RISK FACTORS NO ANTENATAL CHECKUPS 50%(60) HOME DELIVERY 40%(48) FETAL DISTRESS 25%(30) MECONIUM STAINED LIQUOR 23.3%(28) PROLONGED LABOUR 20% (24) PROLONGED RUPTURE OF MEMB 16.7%(20) ANTEPARTUM HAEMORRHAGE 13.3%(16) SEVERE ANEMIA 10%(12) ECLEMPSIA 8.3%(10) PREMATURE RUPTURE 6.6%(8) OF MEMBRANE OBSTRUCTED LABOUR 5%(6) TABLE 2: PERCENTAGE OF NEONATES SHOWING ENCEPHALOPATHY AS PER SARNAT & SARNAT STAGING TOTAL NO OF NEONATES SHOWING ENCEPHALOPATHY 80(66.6%) STAGE 2 30%(36) STAGE 1 20%(24) STAGE 3 16.6%(20) TABLE 3: CLINICAL FEATURES OF NEONATES WITH PERINATAL ASPHYXIA FEEDING DIFFICULTIES 90(75%) RESP DISTRESS 30(25%) MECONIUM ASPIRATION SYNDROME 16(13.3%) ACUTE RENAL FAILURE 10(8.3%) APNOEA 5(4.2%)
In the present study, we had 101 cases with history of meconium stained amniotic fluid out of which 77.2% cases developed meconium aspiration syndrome. This was much higher percentage as compared to the observations by Ashtekar et al.
A pre-designed proforma was filled by reviewing of clinical notes which entailed information about basic demographic information gestational age, birth weight, gender of baby, booking status of mother, maternal clinical characteristics, medical and obstetric complications during pregnancy, premature rupture of membrane (PROM), grades of meconium, mode of delivery, neonatal outcome (APGAR score, type of resuscitation, meconium aspiration syndrome and need for admission in nursery).
Meconium aspiration syndrome requiring assisted ventilation: Perspective in a setting with limited resources.
Three were born at the hospital with severe birth asphyxia and one had meconium aspiration syndrome.
Objectives: To determine the frequency of complications like air leak syndrome and persistent pulmonary hypertension (PPHN) in neonates with meconium aspiration syndrome in Children Hospital Lahore.
Meconium aspiration syndrome (MAS) was found in 16 (5.33%) neonates and 26 (8.67%) had congenital anomalies (Table 4).
The common ultrasonographic manifestations of TTN are interstitial syndrome or white lungs, DLP, pleural line abnormalities, and A-line disappearance [Figure 7].[sup][14],[49] Although, TTN rarely leads to death, it is necessary to correctly differentiate TTN from other diseases with dyspnea, such as RDS, pneumonia, and meconium aspiration syndrome (MAS), to correctly manage infants with TTN and dyspnea.
Luke suffered from meconium aspiration syndrome at birth and was treated in the NICU for three days.
Trial results showed that 26% of the neonates who were not intubated and suctioned developed meconium aspiration syndrome, compared with 32% of their intubated and suctioned counterparts, a nonsignificant difference, researchers reported at the annual meeting of the Pediatric Academic Societies.