Some of the recent research examples on MCZ are meclizine
hydrochloride mouth dissolving tablets , cyclodextrin-meclizine
HCl inclusion complexes , meclizine
hydrochloride solid dispersions using polyethylene glycol 8000 , meclizine
HCl orally disintegrating tablets , meclizine
-maltodextrin orodissolving tablets .
Initial studies in animals using meclizine
, a drug commonly used to treat nausea and vertigo, have given favourable results in treating cardiovascular diseases and stroke.
Drugs Commonly Used for Treatment of Nausea and Vomiting Dopamine- Antihistamine Drugs Antagonist Drugs Anticholinergic Agents/ Dimenhydrinate Promethazine * Scopolamine (Dramamine[R]) (Phenergan[R]) (Transderm Scop[R]) Meclizine
Prochlorperazine Trimethobenzamide (Antivert[R]) (Compazine[R]) (Tigan[R]) Diphenhydramine Metoclopramide (Benadryl[R]) (Reglan[R]) Droperidol (Inapsine[R]) Chlorpromazine (Thorazine[R]) The FDA recently issued a "black box" warning for promethazine regarding the risks of IV push administration.
Over-the-counter antihistamines, such as meclizine
(Antivert, Bonine), dimenhydrinate (Dramamine), and diphenhydramine (Benadryl) are commonly used for prevention.
The physician had actually prescribed meclizine
to treat the patient's dizziness, but the pharmacist misread the prescription.
The treatment of choice is oral meclizine
at 25 mg every 6 hours or a 1.
Other interventions included a high-protein, high-calorie diet, dietician consultations, supplemental nutritional support, nausea medications such as meclizine
25 mg by mouth every day, and continued evaluation of laboratory values and response to therapy.
The procedure involved the exposure of varying concentrations of meclizine
to early life stages of Xenopus laevis, a South African clawed frog, for 96 hours.
Trussell also recommended discussing the use of nonprescription antinausea medications, such as meclizine
hydrochloride, with patients.
HCl, Promethazine HCl and Venlafaxine HCl tablets add to expanding product portfolio
1]-receptor blocker Dimenhydrinate Not rated Compatible Diphenhydramine Not rated Compatible Doxylamine Not rated Compatible Hydroxyzine Not rated Human data suggest low risk Meclizine
Not rated Compatible Metoclopramide B (35) Compatible Phenothiazine Prochlorperazine Not rated Compatible Promethazine C (36) Compatible Ondansetron B (37) Human data suggest low risk Pyridoxine hydrochloride A (38) Compatible Corticosteroid C (39) Human data suggest risk; Prednisone avoid during first 10 weeks of gestation Abbreviation: FDA, US Food and Drug Administration.
We plan to launch the following by the end of 2013: Lisinopril, meclizine
, ababcavir sulfate, famciclovir, montelukast sodium, pantoprazole Na, phentermine HC1 tablets and capsules, olanzapine and zolmitriptan," notes Ostaficiuk.