, the generic version of Citron's Antivert, is indicated for the treatment or prevention of nausea, vomiting and dizziness caused by motion sickness, with IMS-reported generic sales of USD38m.
works on the chemoreceptor trigger zone and on the histamine receptors in the brain," Dr.
for Prevention of Nausea Associated with Emergency Contraceptive Pills: A Randomized Trial," Obstetrics and Gynecology 95: 271-7.
Some of the recent research examples on MCZ are meclizine
hydrochloride mouth dissolving tablets , cyclodextrin-meclizine HCl inclusion complexes , meclizine
hydrochloride solid dispersions using polyethylene glycol 8000 , meclizine
HCl orally disintegrating tablets , meclizine-maltodextrin orodissolving tablets .
For tests of postural stability, we excluded 2 participants who reported current use of the drug meclizine
and 2 with Meniere's disease.
Anthistamines Diphenhydramine (Benadryl); hydroxyzine (Atarax); cetirizine (Zyrtec); loratadine (Claricin) Sleep medications Diphenhydramine (Tylenol PM) Nausea medications Prochlorperazine (Compazine) Antidepressants Amitriptyline (Elavil); paroxetine (Paxil); fluoxetine (Prozac); mirtazapine (Remeron); trazodone Incontinence drugs Tolterodine (Detrol); oxybutynin (Ditropan) Irritable bowel Dicyclomine (Bentyl) medications Vertigo/seasickness Scopolamine patch (Transderm Scop); drugs meclizine
(Antivert); dimenhydrinate (Dramamine) Muscle relaxants Baclofen Antacids Cimetidine (Tagamet); ranitidine (Zantac) Antidiarrheals Loperamide (Imodium)
: Net sales for fourth quarter were $5.4 million compared to $6.2 million in the previous quarter.
The authors found that in laboratory animals (mice and rats), and in cell culture models, meclizine
(one of two drugs marketed as Dramamine) helped to protect hearts from injury due to decreased blood flow.
After having received a total of five intratympanic dexamethasone injections, the patient reported a subjective stabilization of his hearing bilaterally and satisfactory control of his vertigo with meclizine
. At his final follow-up, he reported no change in hearing and no episodes of vertigo.
One of the key findings of the study was meclizine
, a well-known nausea drug, may help treat heart disease and stroke.
can be used acutely to reduce the over reaction of the vestibular system for central dizziness and Zofran (a very effective anti-emetic) can be utilized for the associated nausea caused by cerebellar or retro-mastoid tumor resections.
However, only meclizine
is indicated as an antiemetic (Adams & Koch, 2010).