mechanistic study

mechanistic study

A study or test designed to analyse the biologic or chemical events responsible for, or associated with, an effect observed, and to provide information concerning the molecular, cellular or physiological mechanisms by which substances exert their effects on living cells and organisms.
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A separate mechanistic study in a different group of psoriasis patients provided a likely explanation for the long relapse-free period seen off therapy in some patients in the extension study.
A better understanding of the roles of chromatin-interacting complexes in such disease states requires a detailed mechanistic study.
Laurent Fischer, MD, chief executive officer of Tobira, said, 'Completion of enrolment in this mechanistic study marks another milestone for Tobira as we explore the full potential of CVC.
However, deaths caused by heart failure were balanced between those on saxagliptin and those on placebo, and no possible mechanism for the HF finding could be identified, according to AstraZeneca, which is planning a mechanistic study to evaluate the effects of saxagliptin on volume, neurohormonal changes, and cardiac function.
Prof Hong Wan Jin, Executive Director of IMCB, said, "Dmitry has been the pioneering driver in the mechanistic study of Wip1 phosphatase, and this discovery is monumental in providing novel understanding on the role of Wip1 in cancer at the genomic and systems levels.
A mechanistic study (one that looks to elucidate a mechanism of action for a drug or product in a biological system), does not always translate to how the product will actually work in a real human being.
The topics include analyzing the mineralogical component of palm oil fuel ash with or without unburned carbon, the effect of different gloss firing temperature on the crystallization of zinc-based crystal glaze, forming a titanium carbide reinforced copper matrix composite by an in situ process, synthetic hydrotalcite prepared from a modified combustion method using glucose as fuel, the formation and mechanistic study of self-ordering zirconium oxide nanotubes by anodic oxidation, and the characterization and phase evolution of cordierite based glass synthesis from pure oxide and minerals.
MECHANISTIC STUDY ON THE DEGRADATION OF GASOLINE OXYGENATES BY ULTRASONIC IRRADIATION.
60) Mechanistic study on the role of para-aramid short fibers in rubber to brass adhesion.
The mechanistic study will be the last to be placed and we have not asked scientists to undertake the work yet.
According to the company, the data from the mechanistic study demonstrated that a single dose of LX4211 significantly increased circulating levels of GLP-1 (active and total) and PYY, important regulators of glycemic and appetite control.