mechanism of action


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mechanism of action

(1) The manner in which a therapeutic agent acts, which includes blocking of receptors, enzymes, stimulating hormone production, etc. 
(2) The physiologic or biochemical processes within the body that are affected by a drug’s action, producing a given response.

mechanism of action

The means by which a drug exerts its effects on cells or tissues. It may have specific binding sites, receptor activation, enzymatic activity, or solubility.
See also: mechanism
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References in periodicals archive ?
The combination of a potentially new mechanism of action and an attractive safety profile makes this compound potentially useful either alone or in combination with existing alternatives.
Hollis-Eden Pharmaceuticals Presents Data Demonstrating Discovery of an Endogenous Hormone Potentially Central to Glucose Metabolism
The results obtained in the CARLA provided evidence for a molecular mechanism of action of the test compounds via hER that is distinct from that of [E.
Estrogenic Activity Assessment of Environmental Chemicals Using in Vitro Assays: Identification of Two New Estrogenic Compounds
Talabostat's mechanism of action is extremely interesting and with the positive results we saw in the Phase 2 non-small cell lung cancer trial, we thought this was a nice opportunity to introduce talabostat to a wider audience," explained Dr.
Talabostat Phase 2 Non-Small Cell Lung Cancer Trial Featured at the 14th International Conference on Gene Therapy of Cancer
The mechanism of action of DPP-4 inhibitors is distinct from that of any currently available class of glucose-lowering agents.
New Phase III Data Showed Significant Glucose-Lowering Efficacy of JANUVIA(TM), an Investigational Medicine for Type 2 Diabetes, When Taken Simultaneously with Metformin
USPRwire, Tue Aug 22 2017] This report provides comprehensive information on the current therapeutic developmental pipeline of TechnoPhage SAs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
TechnoPhage SA - Product Pipeline Review -- 2015 Is Released
Talabostat is a new targeted anti-cancer agent believed to work through a novel dual mechanism of action that inhibits select dipeptidyl peptidases (DPPs).
New Data Supports Talabostat's Ability to Stimulate Key Cytokines Essential to Immunostimulation; Point Therapeutics, Inc. Presents at the 2006 AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development
USPRwire, Mon Aug 21 2017] This report provides comprehensive information on the current therapeutic developmental pipeline of Toleranzia ABs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
Toleranzia AB - Product Pipeline Review -- 2015 Is Released
Through years of research with these compounds -- metabolic conversions or synthetic analogs of adrenal steroid hormones -- Hollis-Eden has made significant discoveries relating to their metabolism, mechanism of action and pharmacologic profile.
Hollis-Eden Pharmaceuticals Presents Data Demonstrating Potential Therapeutic Benefits of Second-Generation Drug Candidates
Panacos has confirmed the mechanism of action of these compounds in additional functional assays.
Panacos Presents Progress on HIV Fusion Inhibitor Program at International AIDS Conference
USPRwire, Tue Jun 27 2017] This report provides comprehensive information on the current therapeutic developmental pipeline of Inventiva SASs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
Inventiva SAS - Product Pipeline Review -- 2015 Is Released

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