Identification of a locus for maturity-onset diabetes
of the young on chromosome 8p23.
Evaluation of common variants in the six known maturity-onset diabetes
of the young (MODY) genes for association with type 2 diabetes.
of the young (MODY) at least 10 times more common in Europe than previously assumed.
of the Young (MODY) is a clinically heterogeneous group of disorders characterized by nonketotic diabetes, an autosomal dominant pattern of inheritance, and typical onset below the age of 25 years.
They also identified genes responsible for myotonic dystrophy (141: 102), maturity-onset diabetes
of the young (141: 300), two forms of the eye disorder macular degeneration (142: 37), and a gene that predisposes women to breast cancer following exposure to extremely low doses of radiation (141: 4).
This has been most clearly demonstrated for several of the genes responsible for the syndrome designated maturity-onset diabetes
of the young (MODY)  (13).
CHICAGO -- Approximately 5% of antibody-negative /C-peptide-positive children and adolescents who are diagnosed with diabetes in the United States may have maturity-onset diabetes
of the young rather than type 2 diabetes, Dr.
Other research by his team suggests that identification of two phenotypes of maturity-onset diabetes
of the young (MODY) can allow beneficial changes in treatment--even in patients who have had up to 30 years of suboptimal therapy.
Between 100,000 and 500,000 people in the United States suffer from maturity-onset diabetes
of the young (MODY), an uncommon form of Type II diabetes that develops before age 25.
Mutations in the glucokinase gene lead to an impaired sensing of blood glucose by the pancreatic [beta] cell, causing an autosomal dominant form of type 2 diabetes, maturity-onset diabetes
of the young type 2 (MODY2).
Mutations in the hepatocyte nuclear factor-4 alpha gene in maturity-onset diabetes
of the young (MODY1).