maturity-onset diabetes


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Type 2 di·a·be·tes

(tīp dī-ă-bē'tēz)
A condition characterized by high blood glucose levels caused by either a lack of insulin or the body's inability to use insulin efficiently. Type 2 diabetes develops most often in middle-aged and older adults but can appear in young people.
Synonym(s): maturity-onset diabetes, non-insulin-dependent diabetes mellitus.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

maturity-onset diabetes

DIABETES MELLITUS developing in or after middle age and caused by a relative insufficiency of INSULIN production by the PANCREAS. The condition is of more gradual development than insulin-dependency diabetes and can often be treated by diet or oral HYPOGLYCAEMIC drugs rather than by insulin. In general, it is associated with less severe symptoms than juvenile-onset (Type I) diabetes, but complications such as eye and kidney disease are common. Also known as Type II diabetes.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Molecular diagnosis of maturity-onset diabetes of the young (MODY) in Turkish children by using targeted next-generation sequencing.J Pediatr Endocrinol Metab 2015;28:1265-71.
The clinical management of hyperglycemia in pregnancy complicated by maturity-onset diabetes of the young.
Li et al., "Long-term renal changes in the liver-specific glucokinase knockout mouse: implications for renal disease in maturity-onset diabetes of the young 2," Translational Research, vol.
Love et al., "Frequency and genetic spectrum of maturity-onset diabetes of the young (MODY) in southern New Zealand," Journal of Diabetes and Metabolic Disorders, vol.
Velho, "Diagnosis and management of maturity-onset diabetes of the young," Treatments in Endocrinology, vol.
Polonsky, "Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young," New England Journal of Medicine, vol.
(8) Another example where the specific genetic variant determines clinical presentation and treatment response is maturity-onset diabetes of the young (MODY).
Categories of diabetes in the young include early-onset type 2 diabetes, maturity-onset diabetes of the young (MODY), and type 1 immune-mediated diabetes (1).
(2.) Winter WE, McLaren NK, Riley WJ, Clarke DW, Kappy MS, Spillar RP: Maturity-onset diabetes of youth in black Americans.
CHICAGO -- Approximately 5% of antibody-negative/C-peptide-positive children and adolescents diagnosed with diabetes in the United States may have maturity-onset diabetes of the young rather than type 2 diabetes, Dr.
* Diagnosis of hemochromatosis, early-onset Alzheimer's and Parkinson's disease, colorectal and breast cancers, rare forms of amyotrophic lateral sclerosis, maturity-onset diabetes of the young, hearing loss and deafness.

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