Revision of the ADA-classification of diabetes mellitus type 2 (DMT2): The importance of maturity onset diabetes
(MOD), and senile diabetes (DS).
The other types are type 2 diabetes, neonatal diabetes, maturity onset diabetes
of young, drug induced diabetes, diabetes due to the disease of exocrine pancreas and genetic syndromes associated with diabetes.
Diabetologists have also been aware of the transmissibility of diabetes in families, as in the cased of maturity onset diabetes
of the young (MODY)11.
Characteristics of maturity onset diabetes
of the young in a large diabetes center.
Childhood T2D can be confused with maturity onset diabetes
of the young (MODY) due to the presence of a family history, presenting features and a possible confounding factor of obesity/overweight (5,6).
Owen, "Diagnosis and management of maturity onset diabetes
of the young (MODY)," BMJ, vol.
Common variants in maturity onset diabetes
of the young genes contribute to risk of type 2 diabetes in Finns.
Abbreviations CVD: Cardiovascular diseases CHD: Coronary heart disease GDM: Gestational diabetes mellitus GIP: Glucagon intestinal peptide GLP: Glucagon-like peptide 1 IADPSG: International association of diabetes and pregnancy study groups MODY: Maturity onset diabetes
of the young ORs: Odds ratios OXLDL: Oxidized LDL SNPs: Single nucleotide polymorphisms T2DM: Type 2 diabetes mellitus TG: Triglycerides.
LAN HAM, M.D.., January 31, 2013--Scientists have for the first time generated human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes
of the young (MODY).
[30,31] Although this approach had proven extremely successful in identifying rare genetic variants of strong effects for single-gene disorders such as maturity onset diabetes
of the young (MODY), but proved limited in unveiling common genetic variants that underlie polygenic diseases.
Corcoy, "Maturity onset diabetes
of the young and pregnancy," Best Practice & Research.
Maturity Onset Diabetes
of the Young, or MODY, is worth considering in white youth who are pancreatic autoantibody-negative and have a history of parental non-type 1 diabetes.