mature teratoma


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to mature teratoma: dermoid cyst

mature teratoma

A tumour that maintains an orderly arrangement, with well-differentiated ectodermal and mesodermal tissues surrounding endodermal components. Most mature teratomas have a cystic cavity lined by epithelial cells, and are typically filled with sebaceous secretions and hair. While they are usually benign, malignant degeneration in the form of squamous cell carcinoma are well described.
References in periodicals archive ?
Conclusively, nasopharyngeal mature teratomas are an otolaryngology urgency in terms of localization and clinical picture especially in newborns, although they are observed considerably rarely and have benign properties.
Other studies from Khyber Pakhtunkhwa province by Sumaira et al7 and Samina et al8 showed the frequency of mature teratoma to be 18% and 19.
In a study comprising of 126 patients, recurrence of tumor was seen in 11% of cases with mature teratoma during the five year follow-up.
Gliomatosis peritonei (GP) is a fascinating condition whereby immature and, less often, mature teratomas become associated with a myriad of peritoneal nodular or miliary implants composed of mature glia.
The patient was examined by chest computed tomography (CT), which disclosed a 20cmx12cmx9cm peripherally calcified cystic mass occupying a majority of the anterior mediastinum, highly suggestive of mediastinal mature teratoma.
Mature teratoma is the third most common ovarian tumour in this study.
Mature teratoma show lining of cuboidal epithelium and nests of squamous cells, and spindle-shaped mesenchymal cells in stroma with foci of cartilage are seen.
Histopathology of this mass revealed no viable tumour but mature teratoma elements were seen.
The diagnosis of GTS, first described in 1982, is based on three criteria: [1] (i) an increase in tumour size or detection of metastases during or after chemotherapy for malignant germ cell tumour; (ii) normal tumour markers (which were high initially); and (iii) mature teratoma without evidence of malignancy on histopathology of the post-chemotherapy surgical specimen.
Till date all reported cases are of mature teratoma this case report is 1st report of grade III immature placental teratoma based on Prominent immature neoplastic neuroepithelial elements with true and pseudorossette formation mixed with other mature and immature cells and tissue elements of all three germ layers were seen.