mature teratoma


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Related to mature teratoma: dermoid cyst

mature teratoma

A tumour that maintains an orderly arrangement, with well-differentiated ectodermal and mesodermal tissues surrounding endodermal components. Most mature teratomas have a cystic cavity lined by epithelial cells, and are typically filled with sebaceous secretions and hair. While they are usually benign, malignant degeneration in the form of squamous cell carcinoma are well described.
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References in periodicals archive ?
The prognosis of mature teratomas of the mediastinum is excellent after complete resection.
Mature teratomas are often asymptomatic and rarely invade the pericardium.
Mature teratomas are benign and they do not lead to invasion or metastasis in the surrounding tissues.
Mature teratoma termed as dermoid cyst by the clinicians accounts for nearly one third of all benign ovarian neoplasms.12 They consist of adult-type differentiated components such as skin cartilage and glandular epithelium.3
As discussed above, mature teratoma is benign, but immature teratoma has some potential for malignant behavior.
Mature teratoma is the third most common ovarian tumour in this study.
Histology of residual masses after first-line chemotherapy will be necrosis in 40% to 50%, mature teratoma in 35% to 40% and viable cancer in 10% to 15%.[sup.124,125] The incidence of viable cancer is likely even higher after salvage chemotherapy.[sup.124,126] Some of the factors that have been found to predict for no viable tumour in the residual mass include: no teratoma in the primary tumour, pre-chemotherapy normal tumour markers, a small pre-chemotherapy mass, a large shrinkage of the mass with chemotherapy, and size of residual mass [less than or equal to] 10 mm.[sup.125,127,128] To date, however, no imaging procedures, including PET scan, nor any one predictive factor or predictive model exists to reliably predict the histology of residual masses.[sup.125,127]-[sup.133]
[2] A malignant tumour that arises in a pre-existing mature teratoma is called teratoma with malignant transformation, [3] which occurs in 1-3% of all mature teratomas.
Parapharyngeal space is an uncommon site for mature teratoma and very few cases have been reported in adults and children.
Imaging alone was the modality of investigation which confirmed cases like mature teratoma, aneurysm of ascending aorta and mediastinal lipomatosis; 9 of 30 cases were NHL, 8 of them located in anterior mediastinum.
It is a benign mature teratoma showing components of all three germinal layers without any immature elements.