segmented neutrophil

(redirected from mature neutrophil)

seg·ment·ed neu·tro·phil

a fully matured neutrophil that has at least two (and as many as five) distinct lobes in the nucleus and manifests active ameboid motion.
Synonym(s): mature neutrophil
Farlex Partner Medical Dictionary © Farlex 2012

seg·ment·ed neu·tro·phil

(seg-ment'ĕd nū'trō-fil)
A mature and fully functional polymorphonuclear leukocyte (PMN) containing cytoplasmic granules (primary or azurophil and secondary or specific) and a lobulated chromatin-dense nucleus with no nucleolus.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Promyelocyte, myelocyte, metamyelocyte, band and mature neutrophil forms were absent.
G-CSF is a glycoprotein that influences the survival, proliferation, differentiation, and function of mature neutrophil granulocytes and their precursors [9].
The researchers counted 200 mature neutrophils and expressed them as a percentage of toxic granulated neutrophils in mature neutrophil group.
Laboratory blood tests at hospital admission showed a leukocyte count of 13,400 cells/[mm.sub.3] (with a mature neutrophil count of 87%), hemoglobin of 10.8 g/dL, and a platelet count of 611,000 cells/[mm.sub.3]; electrolyte levels and results of liver function tests were normal, but a total cholesterol count of 267 mg/dL and a triglyceride level of 440 mg/dL were found.
Neutrophils derived from bone marrow hematopoietic stem cells, which undergoes multiple developmental stages, such as myeloblast, premyelocyte, myelocyte, metagranulocyte, band neutrophils, and eventually develop into mature neutrophils. Neutrophils are the main component of leukocytes in the human circulation, which percentage accounting for 60%~70%, and are the first non-specific immunocytes to arrive at the site of infection through the pathway of transendothelial migration.
Eight of 11 cases (72%) in the study group showed detached intracytoplasmic inclusions in mature neutrophils consistent with Howell-Jolly body-like inclusions (Figure, a through d).
Wide expression of pyrin in mature neutrophils suggests that this protein may provide down regulation of the inflammation mediators (26,27).
IL-3, which activates mature neutrophils and macrophages, was also significantly decreased.
Bone marrow analysis revealed a maturation arrest at the promyelocyte/myelocyte stage with few mature neutrophils; there was no evidence of malignant involvement in the bone marrow.
Classical Sweet's syndrome is characterized by the physical findings described above with a diffuse infiltrate consisting predominantly of mature neutrophils located in the upper dermis on pathology.
Her total count was 22000 per cu.mm, predominant were mature neutrophils and stab forms (Figure 4).
Soon, however, our body runs out of mature neutrophils and begins pushing immature ones into our system.