Our results demonstrate that AUB-induced AHR is dependent upon lymphocytes because AHR is significantly attenuated in mice lacking mature lymphocyte
populations ([RagI.sup.[-/-]] mice).
These blast are 3-4 times the size of mature lymphocyte
with scant to moderate account of cytoplasm and occasional; blast showing Auer Rods.
Histopathology of specimen showed diffuse sheeth of uniformly size round cells with large round vesicular nuclei and abundant pale eosinophilic cytoplasm, thin fibrous septa shows mature lymphocyte
infiltrates suggestive of classical seminoma (pic-2).
D, Higher magnification showing mature lymphocytes
, scattered larger atypical lymphocytes, and rare plasma cells (hematoxylin-eosin, original magnifications X4 [A], X20 [B and C], and X40 [D]).
Peripheral Smear showing Mature Lymphocytes
and Smudge Ceiis (ALC= 19400 ceiis/[mm.sup.3]): a.
Flow cytometry (FCM) further confirmed the existence of P1 cells, mature lymphocytes
, and myeloid cells in peripheral blood.
Specifically, many scattered large atypical cells are distributed throughout the infiltrate within a background of abundant small- to medium-sized mature lymphocytes
P53 mutations appeared as common genetic trait in breast medullary carcinoma which showed common features with other lymphoepithelioma-like carcinoma including syncytial sheet of large pleomorphic cells without glandular differentiation and numerous mature lymphocytes
and plasma cells in the adjacent stroma [26, 27].
B) High magnification view showing an angiocentric epithelioid granuloma cuffed by mature lymphocytes
(original magnification x 200).
A May-Griinwald-Giemsa-stained peripheral blood film revealed typical small mature lymphocytes
with condensed chromatin, with less than 10% of prolymphocytes.
The myeloid series of cells showed 52% blasts, only 5% mature lymphocytes
, and 1% plasma cells [Figure 3].
On cytologic evaluation of the sample, a monomorphic population of small, mature lymphocytes
representing >30% of the total number of cells was identified.