matrix vesicles

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matrix vesicles

hydroxyapatite-containing, membrane-enclosed vesicles secreted by odontoblasts, osteoblasts, and some chondrocytes; believed to serve as nucleation centers for the mineralization process in dentin, bone, and calcified cartilage.

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Cai et al., "Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release," Kidney International, vol.

Activation of CD137 Signaling Enhances Vascular Calcification through c-Jun N-Terminal Kinase-Dependent Disruption of Autophagic Flux

In fact, recent research has shown that calcitriol accelerates matrix vesicle formation in osteoblasts but only during the early phase of differentiation [23].

Differential Effects of Calcitriol, FGF-23, and Klotho on Vascular Smooth Muscle Cell Calcification and Their Role in Medial Calcification

Notably, electron micrograph captures an osteoblast matrix vesicle just as it initiated the exocytosis of hydroxyapatite (EDX spectrum).

Rapid Rapamycin-Only Induced Osteogenic Differentiation of Blood-Derived Stem Cells and Their Adhesion to Natural and Artificial Scaffolds

Tague, "The role of matrix vesicles in growth plate development and biomineralization," Frontiers in Bioscience, vol.

Extracellular Vesicles and Autophagy in Osteoarthritis

Biomineralization and matrix vesicles in biology and pathology.

Association Between Dentin Matrix Protein 1 (rs10019009) Polymorphism and Ankylosing Spondylitis in a Chinese Han Population from Shandong Province

Because calcifiable vesicles may have a role in plaque calcification (38), much work has been done on phospholipid vesicles as substitutes of matrix vesicles in simulative biomineralization research.

Effects of LDL, cholesterol, and their oxidized forms on the precipitation kinetics of calcium phosphates