MMP20(redirected from matrix metalloproteinase-20)
MMP20A gene on chromosome 11q22.3 that encodes matrix metalloproteinase 20, which degrades amelogenin, the major protein of the enamel matrix, and two macromolecules of the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein. MMP20 may play a central role in tooth enamel formation. It is also the retired HUGO symbol for what is now designated MMP25, see there.
Defects in MMP20 cause amelogenesis imperfecta type 2A2.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.