MMP1

(redirected from matrix metallopeptidase 1)

MMP1

A gene on chromosome 11q22.3 that encodes matrix metalloproteinase 1, which cleaves collagens I, II and III in the helical domain, as well as collagens VII and X. MMP1 interacts and cleaves HIV’s secreted Tat protein, reducing neuronal Tat-mediated neurotoxicity.
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References in periodicals archive ?
Yin et al., "Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma," European Journal of Cancer, vol.
Researchers found that the epiregulin, matrix metallopeptidase 1 and 2, and cyclooxygenase-2 genes produce proteins that combine to stimulate the formation of new blood vessels, enabling cancer cells to escape into the bloodstream and lungs.