The method was prone to matrix interference
, with the impact of the sample matrix on the reported result being unknown.
In this paper, we attempted to reduce the matrix interference
utilizing ion-exchange solid phase extraction (SPE) cartridges and successfully met the criterion of method availability.
However, direct determination of such low concentration of elements by FAAS is often difficult, not only due to the limitation associated with the insufficient sensitivity of the analytical instrumentation, but also due to complex formation and high matrix interference
which invariably influence normal instrumental analysis [1, 2].
Therefore, it stands to reason that the probability of matrix interference
occurring is highly likely, considering the multitude of products on the market, all of which contain different materials.
Disadvantages are matrix interference
, and that for most electronics it is difficult or impossible to perform the analysis on homogeneous areas without overlapping other materials on the device.
(2), the filter paper serves to reduce serum sample matrix interference
, a well-known phenomenon in electrospray ionization MS.
Koscielniak  used a technique of injecting the sample and the standard solution one after another into the carrier stream to correct matrix interference
Laboratory procedures were conducted using a spiked distilled water to limit matrix interference
. Raw sulfide-containing water from Pinellas County water treatment plants was used in the field studies.
Most often matrix interference
effects can be overcome by the use of a graphite platform or a matrix modifier.
* differentiate target compounds from matrix interference
The effects of matrix interference
can be overcome by adopting standard addition method.
* Rule out matrix interference
via selectivity experiments, in which different lots of matrix are analyzed after spiking with zero, low, and high concentrations of surrogate antibody