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The "sheltering" coverings of the central nervous system. See: arachnoid mater, dura mater, pia mater.
[L. mother]
Farlex Partner Medical Dictionary © Farlex 2012


A gene located on chromosome 19q13.43 that encodes a member of the NALP protein family, which is only expressed in oocytes and thought to be required for normal early embryogenesis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


The "sheltering" coverings of the central nervous system.
See: arachnoid mater, dura mater, pia mater
[L. mother]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


(mat'er) [L. mater, mother]
Non-neural tissue coverings of the brain and spinal cord; meninges.

arachnoid mater

Arachnoid membrane.

dura mater

The outermost meninx, a tough sheet of fibrous connective tissue that completely envelops the brain and spinal cord inside the skull and vertebral canal. Inside the skull, there is no epidural space, and the dural envelope is fused with the inner periosteum of the skull bones. Inside the vertebral canal, however, the dural envelope is separated from the vertebral bone by an epidural space filled with fat and a network of veins.
Synonym: dural membrane

pia mater

The innermost meninx, adelicate membrane coating the surfaces of the brain and spinal cord and closely following all their surface contours. In most places, the pia mater is one cell thick. It encloses the surface blood vessels of the brain, and it follows the arteries as they dive into the brain tissue. It appears that the pial membrane is part of the blood-brain barrier, a set of physiological constraints that restrict diffusion of many blood-borne molecules into the tissues of the brain.
Synonym: pial membrane
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Mater Engineering developed a plan for the Confederated Tribes of Grand Ronde that shows a potential for about 100 new jobs, harvesting ferns and other forest products for the floral industry.
Plans also include Mater Engineering's special forest products project, according to Bruce Thomas, general manager of Spirit Mountain Development Corp., the tribes' development arm.
To induce degranulation of mast cells in the dura mater, we applied to the dura mater compound 48/80 which is known as a mast cell degranulating agent an IgE-independent manner (24).
By investigating the effects of compound 48/80 induced dural mast cell degranulation on the meningeal vasodilation and mast cell numbers in the ex vivo rat meningeal preparations, we showed that compound 48/80 induced massive degranulation of mast cells in the dura mater and dural mast cell degranulation caused vasodilation of middle meningeal artery and its anterior and posterior branches by increasing the diameters of them, respectively.
In the present study, middle meningeal artery and its branches were chosen due to the relevance for the generation of headaches (1,6), therefore the change in diameter of middle meningeal artery and its branches in response to mast cell degranulation in the dura mater has demonstrated that mast cells in the dura mater play a key role in the pathophysiology of migraine.
A lot of studies reported that direct stimulation of arteries in the dura mater in humans lead to migraine pain like sensations (14).
Therefore currently, migraine scientists have widely accepted that dura mater and neurogenic inflammation in pathophysiology of migraine is important.
Dura mater is the most pain sensitive structure and contains abundant mast cells which are located close proximity to blood vessels in the dura mater (6, 19).
Thus, dural mast cells are related in microvasculature control and regulation of local trigeminal nerve activity in the dura mater (25,28).
Innervation of the dura mater encephali of cat and rat: ultrastructure and calcitonin gene-related peptide-like and substance P-like immunoreactivity.
Morphological and functional demonstration of rat dura mater mast cell-neuron interactions in vitro and in vivo.