Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan
(2009) showed that mastoparan Polybia-MPII, isolated from Polybia paulista wasp venom, resulted statistically significant reduction in the volume fraction of the terminal boutons occupied by synaptic vesicles and also showed that there was an associated reduction in cross-sectional area.
Mastoparan effects in skeletal muscle damage: An ultrastructural view until now concealed.
Miyazawa, "Conformational change of mastoparan
from wasp venom on binding with phospholipid membrane," FEBS Letters, vol.
Helle, "Catestatin (CgA344-364) stimulates rat mast cell release of histamine in a manner comparable to mastoparan
and other cationic charged neuropeptides," Regulatory Peptides, vol.
Giralt, "Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: Melittin, apamin and mastoparan
," Toxins, vol.
For ATP released from cells, after CPZ 50 [micro]M incubation, erythrocytes were diluted 1:100 and incubated with the direct activator of Gi, Mastoparan
7 (4 [micro]M Mas 7).
(5) Three venom components--hyaluronidase, mastoparan
, and phospholipase A1--have been demonstrated to stimulate prostaglandin E2 and weakly enhance IgE and IgG1 in mice, (6,7) and these may have stimulated the humoral response in this flamingo.
Activation of rat peritoneal mast cells by substance P and mastoparan
The phosphorylation of I3-GST, however, was found to be synergistically enhanced by G protein [beta][gamma] subunits and mastoparan
, which is known to mimic agonist-bound receptors.
Interaction of substance P, compound 48180 and mastoparan
with [alpha]-subunit C-terminal of G protein.
Stock solutions of suramin, guanosine, mastoparan
, guanylyl, caffeine, and TMB-8 hydrochloride were prepared in distilled water; K252a, bisindolylmaleimide I, TPA, indolactam V, 1,2 didecanoyl-rac-glycerol, nifedipine, ionophore A23187 free acid, cyclopiazonic acid, and thapsigargin were dissolved in DMSO.