Methylxanthines can be found in coffee, tea, and chocolate and can aggravate mastalgia
by enhancing the cyclin adenosine monophosphate (cAMP) pathway.
Even the slightest disturbance of the E2/P ratio may contribute to the occurrence of FBD with clinical manifestations of mastalgia
and mastodynia, and its correction may improve the quality of life, reduce the frequency of surgical treatments and eventually, the potential risk of developing breast carcinoma.
A number of dietary therapies have been tried, but on subsequent randomised trials have failed to demonstrate a clear advantage in treatment of mastalgia
. [11-13] Oral contraceptives have shown to be protective in benign breast disorders.
The randomised, double-blind, placebo-controlled clinical trial was undertaken through an academic hospital in Iran, with participants being premenopausal, medically well women aged [greater than or equal to] 18 years, with cyclical mastalgia
and a pain score of [greater than or equal to] 3 on the visual analogue scale (VAS).
(CM) or mastodynia typically occurs every month before the start of the menstrual period and is relieved within 7 days of the onset of menses.
Major symptoms were lump with mastalgia
present in 24 (42.1%) patients followed by lump alone in 17 (29.8%) patients (fig-1).
In some studies patient with leiomyoma and using LNG-IUD the ratio of spotting after three months was 61.2% oligomenorrhea 16.6% HMB 5.6%; at the end of the sixth month spotting 24% oligomenorrhea 36% amenorrhea 40% parallel to our findings.Levonorgestrel has given rise to mastalgia
weight gain edema rarely hirsutismus acne headache.Because of the adverse effects the number of those dropping out of our study in LNG-IUD group was three patients (10%) after six months.
might last for more than 7 days in 11% of women .
Some amount of modularity (lumpiness) together with mastalgia
is found in a normal population [6, 7].
Evaluation of a treatment protocol for chronic mastopathy with mastalgia
, Minerva gynecol, 49(6): 271-6.
In fibrocystic disease the breast has areas of lumpiness, and the patient experiences mastalgia
. (5) Nipple discharge represents an uncommon manifestation of breast cancer in pregnancy.
Adverse effects were negligible including nausea, dizziness, amenorrhea, vaginal spotting, and mastalgia
. The adverse effects were comparable in both groups.