Expression and clinical significance of microRNA-21, maspin
and vascular endothelial growth factor-C in bladder cancer.
The natural tumor suppressor protein maspin
and potential application in nonsmall cell lung cancer.
(9) had been incompletely characterised in terms of p63, maspin
, E- and P-cadherin expression, it was possible that the lesion was a low-grade spindle cell metaplastic breast carcinoma (SpCMBC) (24).
Nuclear cytokine-activated IKK[alpha] controls prostate cancer metastasis by repressing maspin
. Nature 2007; 446: 690-694, doi: 10.1038/nature05656.
Gum mastic increases maspin
expression in prostate cancer cells.
mediates the gemcitabine sensitivity of hormone-independent prostate cancer.
expression, angiogenesis, prognostic parameters, and outcome in malignant melanoma," Journal of the American Academy of Dermatology, vol.
For example, using a dCas9-SAM-VPR complex, researchers reactivated a heavily methylated tumor suppressor gene, Maspin
, in lung cancer cells both transcriptionally and translationally, which limited cancer cell growth and apoptosis .
Detection of the placental epigenetic signature of the maspin
gene in maternal plasma.
(3) To our knowledge, S100P, insulin-like growth factor 2 messenger RNA-binding protein-3 (IMP3), maspin
, von HippelLindau gene product (pVHL), SMAD4, CK17, and MUC5AC appear to be better investigated (Table 6), and will be briefly discussed here.
Fox et al., "Decreased levels of mir-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin
and promoting colorectal tumor growth and metastasis in mice," Gastroenterology, vol.
These effects are probably associated with multiple tumor suppressor genes' concurrent downregulation throughout the various stages of tumor progression, including PDCD4, TPM1, maspin
, and PTEN [20, 45].