marker


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marker

 [mahr´ker]
something that identifies or that is used to identify; see also determinant.
cell-surface marker an antigenic determinant found on the surface of a specific type of cell.
tumor marker a biochemical substance indicative of presence of a tumor; ideally, it should be specific, sensitive, and proportional to tumor load. Called also biomarker.

mark·er

(mark'ĕr),
1. A device used to make a mark or to indicate measurement.
2. A characteristic or factor by which a cell or molecule can be recognized or identified.
3. A locus containing two or more alleles that, being harmless, are common and therefore yield high frequencies of heterozygotes, that facilitate linkage analysis.

marker

/mark·er/ (mahrk´er) something that identifies or that is used to identify.
tumor marker  a biochemical substance indicative of neoplasia, ideally specific, sensitive, and proportional to tumor load.

marker

(mär′kər)
n.
1. A biomarker.
2. A genetic marker.

marker

Medspeak
A value or indicator of the presence of a disease.

Molecular biology
An identifiable physical location on a chromosome (e.g., restriction enzyme cutting site, gene, minisatellite, microsatellite), the inheritance of which can be monitored. Markers can be an expressed region of DNA (gene encoding a protein) or a segment of DNA with no known coding function but whose pattern of inheritance can be determined. A marker can be localised to a specific region of the genome (e.g., all markers on the human transcript map are STSs).

Markers have also been defined as a genetic trait, of which one allelic form is selected or screened for after recombination. 

Suicidology
A potential physiologic indicator or predictor of an increased risk of suicide, the most promising of which is a decrease in serotonin in the brain.

marker

Internal medicine A diagnostic indicator for presence of a disease. See Biomarker, Bone marker, Breast marker, Cardiac marker, Cell marker, Cell surface marker, Gene marker, Genetic marker, Kinesic marker, Microsatellite marker, Pan B-cell marker, Pan T-cell marker, Selectable marker, Selected marker, Surface marker, Surrogate marker, Tumor marker.

mark·er

(mahrk'ĕr)
1. A device used to make a mark or to indicate measurement.
2. A characteristic or factor by which a cell or molecule can be recognized or identified.
3. A locus containing two or more alleles that, being harmless, are common and therefore yield high frequencies of heterozygotes that facilitate linkage analysis.

marker

1. A trait, condition, gene, or substance that indicates the presence of, or a probable increased predisposition to, a medical or psychological disorder.
2. A gene whose location on a chromosome is known so that it can be used as a point of reference for MAPPING new mutations.

marker

see GENETIC MARKER.

mark·er

(mahrk'ĕr)
1. A device used to make a mark or to indicate measurement.
2. A locus containing two or more alleles that, being harmless, are common and therefore yield high frequencies of heterozygotes, which facilitate linkage analysis

marker

a visual or electronic signal that permits identification and therefore sorting of individual items from a group.

marker animals
males or teasers wearing chin-ball or siresine harness so that females mounted are marked by crayon or paint.
marker genes
genes with a known location on a chromosome and an obvious phenotype which are used as reference points when mapping other genes.
histochemical marker
marking of cells or tissues based on a chemical identification of the contents; the location of specific chemical substances in particular locations is marked by the installation of an electronic or color signal.

Patient discussion about marker

Q. what is a safe tumor marker number range?

A. depends on the marker...most of the markers are materials that found normally in our body. and there are a number of markers and their levels differentiate. what marker do you mean?

Q. My wife(53) has elevated CEA and CA19.9 levels - near 150, without any concomitant reason/observation? Comment

A. Hi Bobby3,

The most important question is why were these tests done?
An elevated level may result from many causes, some of them are simple and some are more problematic. IMHO the best thing would be consulting her doctor to consider the need to check-up her alimentary system.
You can read more here (http://www.ascocancerfoundation.org/patient/ASCO+Resources/Patient+Guides/ASCO+Patient+Guide:+Tumor+Markers+for+Gastrointestinal+Cancers) and here (http://www.cancer.gov/cancertopics/factsheet/Detection/tumor-markers)

More discussions about marker
References in periodicals archive ?
2] Nonstandard abbreviations: NRI, Net Reclassification Index; STROBE, Strengthening the Reporting of Observational Studies in Epidemiology; STARD, Standards for Reporting of Diagnostic Accuracy; REMARK, Reporting Recommendations for Tumor Marker Prognostic Studies; MIAME, Minimum Information about a Microarray Experiment; CONSORT, Consolidated Standards of Reporting Trials.
We used two marker sets to calculate ankle angles for comparison with those measured using the potentiometer: a standard HH marker set and an RE marker set.
When a marker is found, the reflected signal causes the receiver to give the operator both a visual reading and an audible tone.
Conclusion: Biochemical markers of bone turnover along with measurements of bone density can help optimize the management of osteoporosis.
Stewart has been told by Nevada veterans officials that her husband soon will receive a marker engraved with a pentacle to be placed at the Northern Nevada Veterans Memorial Cemetery.
The posts for post-mounted markers should be made from 24-gauge steel, aluminum or fiberglass.
But perhaps Kobayashi's biggest epiphany came in 1984-86, when he analyzed serum samples from the Mayo Clinic, in Minneapolis, USA, and discovered a new complex tumor marker and multivariate analysis formula.
Marker soon found that these shepherds have a knack for keeping cheetahs at bay too.
Two kinds of strategies including flanking markers selection and MBLUP selection were adopted aiming at non-specific marker in the paper, so as to provide the reference for implementing marker-assisted introgression in practice.
The default ARToolkit algorithm is to consider the first found marker as a so-called base marker.
Row 5 (neck and raglan inc row, RS): K1, M1, [k2tog tbl, yo] to 1 st before marker, *k1, yo, sl marker, k1, sl marker, yo, [k2tog tbl, yo] to 1 st before marker; rep from * twice more, k1, yo, sl marker, k1, sl marker, yo, [k2tog tbl, yo] to last 2 sts, k1, M1, k1; 35 (35, 37, 37) sts for back, 6 sts for each front, 9 (11, 11, 13) sts for each sleeve, 69 (73, 75, 79) sts total.
sup][3],[5] To the best of our knowledge, limited data regarding the usefulness of sonographic-guided percutaneous fiducial marker implantation for hepatic malignancies.