march hemoglobinuria

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Related to march hemoglobinuria: Runner's Macrocytosis


the presence of free hemoglobin in the urine. adj., adj hemoglobinu´ric.
march hemoglobinuria hemolysis caused by repeated uncushioned shocks or trauma to some body part, such as in some soldiers on long marches, in marathon runners, and in karate practitioners.
paroxysmal cold hemoglobinuria an autoimmune or postviral disease in which there is a biphasic IgG antibody directed against the P blood group antigen. It is marked by episodes of hemoglobinemia and hemoglobinuria after exposure to cold and is detected by the Donath-Landsteiner test. The condition is treated with prednisone and cyclophosphamide and by protection from exposure to cold.
paroxysmal nocturnal hemoglobinuria (PNH) an acquired blood cell abnormality with proliferation of abnormal red blood cells (PNH cells) that are readily hemolyzed by complement, and episodes of severe hemolysis and thrombosis, particularly of the hepatic veins. It is detected by the ham test. Treatment is with androgens or prednisone and, during thrombotic episodes, with heparin.

march he·mo·glo·bi·nu·ri·a

a form occurring after marathon races, protracted marching, or heavy physical exercise.

march hemoglobinuria

Exertional rhabdomyolysis An episodic hemoglobinuria due to hemolysis caused by repeated mechanical injury to RBCs that travel through small vessels overlying the bones of hands and feet in long-distance marching–soldiers, marathon running, calisthenics, karate Lab Myoglobinuria, proteinuria, ↑ BUN, ↑ enzymes–creatinine phosphokinase, ↑ lactic acid

march he·mo·glob·i·nu·ri·a

(mahrch hē'mō-glō'bi-nyūr'ē-ă)
A form occurring after marathon races, protracted marching, or heavy physical exercise.