SOD2(redirected from mangano-superoxide dismutase)
SOD2A gene on chromosome 6q25.3 that encodes a mitochondrial superoxide dismutase which binds superoxide byproducts of oxidative phosphorylation, converting them to hydrogen peroxide and diatomic oxygen.
SOD2 mutations are associated with idiopathic cardiomyopathy, premature ageing, sporadic motor neurone disease, and cancer.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.