Manganese poisoning | definition of manganese poisoning by Medical dictionary
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manganese (Mn) [mang´gah-nēs]
a chemical element, atomic number 25, atomic weight 54.938. (See Appendix 6.) Its salts occur in the body tissue in very small amounts and serve as activators of liver arginase and other enzymes.
manganese poisoning a condition usually caused by inhalation of manganese dust; symptoms of chronic exposure include mental disorders accompanying a syndrome resembling Parkinson's disease, and inflammation throughout the respiratory system.
manganese poisoning Acute or chronic intoxication due to manganese excess.
Industrial exposure to manganese-laden fumes and dusts in mining, steel foundries, welding, and battery manufacture.
Acute—pneumonitis; chronic—psychotic or schizophrenia-like episodes, parkinsonism, movement disorders.
O2 administration, supportive care.
manganese poisoning Acute or chronic intoxication due to manganese excess Etiology Industrial exposure to manganese-laden fumes and dusts in mining, steel foundries, welding, battery manufacture Clinical Acute–pneumonitis; chronic–psychotic or schizophrenia-like episodes, parkinsonism, movement disorders Management O2 administration, supportive. See Manganese.
manganese poisoning An industrial disease largely confined to miners who breathe manganese ore dust and workers exposed to manganese compounds. Brain damage occurs, resulting in rigidity of the muscles with loss of facial expression, slowness of movement, speech impairment, and delusions, hallucinations and compulsive disorders.
References in periodicals archive
and others working near welding or pipefitting activity, are at an increased risk of manganese poisoning
leading to Parkinson's disease, (3) provide compensation to all victims for death and personal injuries, (4) provide a medical monitoring fund for individuals who have shown symptoms of Parkinson's disease.
Neuropsychiatrie manifestations of chronic manganese poisoning
Together with dopamine, manganese can accelerate oxidation-reduction reactions, producing reactive oxidative molecules such as hydrogen peroxide and superoxide free radicals; this potentially explains the dopaminergic neurotoxicity seen in chronic manganese poisoning
and the relief of symptoms by the administration of L-dopa in some patients (10-14).