Developmental toxicity of mangafodipir
trisodium and manganese chloride in Sprague-Dawley rats.
Kim, "MRI for detection of hepatocellular carcinoma: comparison of mangafodipir
trisodium and gadopentetate dimeglumine contrast agents," American Journal of Roentgenology, vol.
Pajaud et al., "Pretreatment with mangafodipir
improves liver graft tolerance to ischemia/ reperfusion injury in rat," PloS One, vol.
Detection of Liver Metastases from Adenocarcinoma of the Colon and Pancreas: Comparison of Mangafodipir
Trisodium - Enhanced Liver MRI and Whole - Body FDG PET.
PledPharma has restarted recruitment on a clinical trial of mangafodipir
in treatment outcomes during angioplasty.
The efficacy of PledOx in reducing serious side-effects of oxaliplatin has been compared with that of another PLED-derivative, mangafodipir
, in a preclinical model.
One of the earliest HPB agents available was Mangafodipir
Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir
. J Natl Cancer Inst, 2006, 98, 236-244.
5.) Contrast agents used for MR imaging of the liver are gadopentetate dimeglumine (GDTPA) and mangafodipir
, manganese dipyridoxyl diphosphate, MnDPDP) or nonchelated forms (e.g.
The older of the 2 agents is mangafodipir
trisodium (TESLASCAN, GE Healthcare, Chalfont St.
The liver-specific contrast agent mangafodipir
trisodium (Teslascan, GE Healthcare, Princeton, NJ) is excreted via the biliary system and T1W MRI after injection of this agent may be useful in the diagnosis of a bile leak.