hyperplasia associated with acromegaly and hyperprolactinemia in a patient with the McCune-Albright syndrome.
13) In the literature, a distinction had been made between mixed GH-PRL and mammosomatotroph
adenomas, especially at large specialty referral institutions, such as that of one of the authors (M.
Subclassification of GHand prolactin-producing adenomas as densely granulated somatotroph adenomas with prolactin content, mammosomatotroph
adenomas, or mixed somatotroph-lactotroph adenomas can be difficult without ultrastructural analysis, but the significance of these subtleties for clinical management remains unclear.