malignant hypertension


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Related to malignant hypertension: essential hypertension, benign hypertension

ma·lig·nant hy·per·ten·sion

severe hypertension that runs a rapid course, causing necrosis of arteriolar walls in kidney, retina, etc.; hemorrhages occur, and death most frequently is caused by uremia or rupture of a cerebral vessel.

malignant hypertension

the most lethal form of hypertension. It is a fulminating condition characterized by severely elevated blood pressure that commonly damages the intima of small vessels, the brain, the retina, the heart, and the kidneys. It affects more African-Americans than Caucasians and may be caused by a variety of factors, such as stress, genetic predisposition, obesity, use of tobacco, use of oral contraceptives, high intake of sodium, sedentary lifestyle, renal disease, and aging. Many patients with this condition exhibit signs of hypokalemia and alkalosis and have aldosterone secretion rates even higher than those associated with primary aldosteronism. Also called accelerated hypertension. See also essential hypertension.
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Malignant hypertension: kidney disease

malignant hypertension

A condition characterised by severe hypertension, retinopathy, renal insufficiency, fibrinoid necrosis of renal arterioles, and rapidly progressive and fatal disease.

Clinical findings
Headache, blurred vision, nausea, vomiting, lethargy.

Risk groups
Males, African Americans, hypertensive patients.
 
Complications
Stroke, MI, blindness, renal failure.

malignant hypertension

Accelerated HTN, arteriolar nephrosclerosis Cardiology A condition characterized by severe HTN, retinopathy, renal insufficiency, fibrinoid necrosis of renal arterioles, rapidly progressive and fatal disease Risk groups ♂, African Americans, hypertensives Clinical Headache, blurred vision, N&V, lethargy Complications Stroke, MI, blindness, renal failure. See Hypertension.

ma·lig·nant hy·per·ten·sion

(mă-lig'nănt hī'pĕr-ten'shŭn)
Severe hypertension that runs a rapid course, causing necrosis of arteriolar walls in kidney and retina, hemorrhages, and death most frequently due to uremia or rupture of a cerebral vessel.

malignant hypertension

A severe and dangerous form of high blood pressure that follows a rapid course with progressive damage to blood vessels and to the eyes and the kidneys. There is a major danger of STROKE. Unless effectively treated the condition is often fatal.

ma·lig·nant hy·per·ten·sion

(mă-lig'nănt hī'pĕr-ten'shŭn)
Severe hypertension that runs a rapid course, causing necrosis of arteriolar walls.
References in periodicals archive ?
In this study, 24% cases of ICSOL in systemic causes followed by 12% cases of meningitis followed by 10% cases of malignant hypertension followed by 8% cases of drug history followed by 6% cases of malaria followed by 2% cases of each diabetes, pseudotumor cerebri, anaemia, encephalopathy and head injury.
Grades 1 and 2 arc chronic whereas grades 3 and 4 indicate acute retinal vascular decompensation and are seen in malignant hypertension (see later).
Ophthalmology exam showing the presence of cotton wool spots and flame hemorrhages consistent with malignant hypertension (see Figure 1).
Malignant hypertension on histology was defined as the presence of fibrinoid necrosis and onion-skinning of the arterioles associated with crenation of the glomerular basement membrane.
Malignant hypertension is a medical emergency with an incidence of 1% in hypertensive patients (1) and is more common in the African American population (2).
There are also choroidal changes seen in malignant hypertension, with focal occlusion of the choriocapillaris leading to necrosis and atrophy of the retinal pigment epithelium (RPE), forming Elschnig's spots.
Before the introduction of captopril in the mid-1980s, nearly 30% of scleroderma patients died from malignant hypertension complicated by renal failure.
He went on to state, "Commercially, the product's pharmacological and clinical attributes make it an ideal candidate for Phase 3 testing in a range of hospital indications including malignant hypertension, and the control of blood pressure during and after cardiac surgery, percutaneous coronary intervention and other acute interventions where precise control of blood pressure is clinically important.
Methamphetamine use is associated with malignant hypertension, mesangiocapillary glomerulonephritis and chronic kidney disease (CKD).
Papilloedema is characteristic of malignant hypertension.
Among the secondary disorders that can result in abrupt headache onset are subarachnoid or intraparenchymal hemorrhage, ischemic stroke, intracranial mass lesion, arterial dissection, meningoencephalitis, malignant hypertension, sinusitis, glaucoma, and venous sinus thrombosis, most of which are medical emergencies.

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