malignant giant cell tumour

malignant giant cell tumour

A nonspecific term for any malignant tumour characterised by myriad giant cells of virtually any lineage.

Examples
Carcinoma with giant cells (thyroid, pancreas, lung), melanoma, giant cell soft tissue osteosarcoma, giant cell fibrosarcoma, leiomyosarcoma with osteoclast-like giant cells.
 
DiffDx
Aneurysmal bone cyst, chondroblastoma, hyperparathyroidism.
References in periodicals archive ?
There was one case of malignant giant cell tumour of humerus, which showed cortical permeation and an associated soft tissue mass as shown by Murphey et al.
The terms of malignant giant cell tumours of soft tissues, giant cell sarcoma, giant cell undifferentiated pleomorphic sarcoma and malignant osteoclastoma are synonyms used for this variant.

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