malignant exocrine pancreatic tumour

malignant exocrine pancreatic tumour

A general term for any malignancy—generally understood to be of epithelial and/or neuroendocrine origin (i.e., non-lymphoid, non-mesenchymal, non-melanoma)—of the exocrine pancreas, which was classified by the World Health Organization in 2000.

Malignant exocrine pancreatic tumours, per WHO
• Ductal adenocarcinoma:
   – Mucinous non-cystic carcinoma (colloid adenocarcinoma);
   – Signet-ring cell carcinoma;
   – Adenosquamous carcinoma;
   – Undifferentiated (anaplastic or sarcomatoid) carcinoma;
   – Undifferentiated carcinoma with osteoclast-like giant cells;
   – Mixed ductal-endocrine carcinoma;
   – Hepatoid carcinoma Not in 2000 WHO classification;
   – Medullary carcinoma Not in 2000 WHO classification.
• Serous cystadenocarcinoma.
• Mucinous cystadenocarcinoma (non-invasive).
• Mucinous cystadenocarcinoma (invasive).
• Mucinous neoplasm (Not in 2000 WHO classification):
   – Mucinous cystic neoplasm (carcinoma in situ);
   – Mucinous cystic neoplasm with invasive carcinoma.
• Intraductal papillary mucinous neoplasm (non-invasive/carcinoma in situ).
• Intraductal papillary mucinous neoplasm with invasive carcinoma.
• Oncocytic variant of intraductal papillary neoplasm (Not in 2000 WHO classification).
• Intraductal tubular neoplasm (Not in 2000 WHO classification).
• Acinar cell carcinoma:
   – Acinar cell cystadenocarcinoma;
   – Mixed acinar-endocrine carcinoma.
• Pancreatoblastoma.
• Solid-pseudopapillary carcinoma.
• Carcinomas of ampulla of Vater, extrahepatic bile ducts.
• Adenocarcinoma.
• Papillary adenocarcinoma.
• Adenocarcinoma, intestinal type.
• Adenocarcinoma, gastric foveolar type.
• Mucinous adenocarcinoma.
• Clear cell adenocarcinoma.
• Signet-ring cell carcinoma.
• Adenosquamous carcinoma.
• Squamous cell carcinoma.
• Small cell carcinoma.
• Undifferentiated carcinoma.
• Mixed carcinoid-adenocarcinoma.
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