angiosarcoma(redirected from malignant angioendothelioma)
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A rare malignant neoplasm occurring most often in soft tissue; believed to originate from the endothelial cells of blood vessels; microscopically composed of spindle-shaped cells, some of which line small spaces resembling vascular clefts.
A malignant tumor arising from vascular tissue.
angiosarcomaAn uncommon, aggressive mesenchymal malignancy, arising in the skin, liver, breast, soft tissues and viscera, primarily affecting the elderly; male:female, 2:1.Aetiology Most are idiopathic; some are linked to chronic lymphoedema (as occurs following axillary dissection for breast CA), others to radiation therapy; hepatic angiosarcoma is classically linked exposure to thorium dioxide (a long obsolete contrast medium), and is also associated with arsenic and vinyl chloride.
Prognosis Poor, 10–20% 5-year survival.
A rare malignant neoplasm occurring most often in the breast and skin, and believed to originate from the endothelial and fibroblastic cells of blood vessels; microscopically composed of closely packed round or spindle-shaped cells, some of which line small spaces resembling vascular clefts.