This case illustrates the importance of correlating pertinent laboratory results to the patient's clinical presentation in the assessment of male hypogonadism
. Because the common symptoms associated with hypogonadism (e.g., low libido, erectile dysfunction, decreased vitality, depressed mood) are nonspecific, serum testosterone determination is important in the workup and diagnosis of hypogonadism.
This report provides comprehensive information on the therapeutic development for Male Hypogonadism
, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
(2005) Clomiphene citrate effects on testosterone/estrogen ratio in male hypogonadism
. The Journal of Sexual Medicine, 2(5), 716-721.
Explaining the process, known as male hypogonadism
, urologist Dr Robert Brannigan of Chicago's Northwestern Memorial Hospital said: "This is a highly prevalent disorder.
: an update on diagnosis and treatment.
MacroChem is a specialty pharmaceutical company with two clinical development stage products containing our proprietary enhancer, SEPA: EcoNail, to treat fungal infection of the nail and Opterone, to treat male hypogonadism
. In addition to our SEPA technology, we are also evaluating applications for MacroDerm, our patented series of polymers that impede penetration of active ingredients through the skin.
: Causes, genetics, diagnosis and treatment
The December 2002 license agreement related to the commercialization of Fortigel, Cellegy's testosterone gel product candidate for the treatment of male hypogonadism
, in North American markets.
Arnason, "Male hypogonadism
and osteoporosis: the effects, clinical consequences, and treatment of testosterone deficiency in bone health," International Journal of Endocrinology, Article ID 4602129, 2017.
As expected, male hypogonadism
is correlated with losses in bone quality, yet unexpectedly, the connection is not tightly dependent on testosterone levels.
Hormonal therapies for prostate cancer, male hypogonadism
as well as endometriosis are also under development.
is a clinical syndrome characterized by symptoms (i.e., fatigue, low energy) in conjunction with decreased serum testosterone levels.