malate synthase

ma·late syn·thase

an enzyme catalyzing the reversible condensation of acetyl-CoA with glyoxylate and water to form l-malate and coenzyme A; an enzyme in the glyoxylate cycle.

malate synthase

An enzyme that catalyses the reaction:
acetyl-CoA + H2O + glyoxylate <—> (S)-malate + CoA.
References in periodicals archive ?
Isocitrate lyase (EC 4.1.3.1) and malate synthase (EC 2.3.3.9) are the sole enzymes for this metabolic pathway.
Further, glyoxylate condenses with a second acetyl-CoA molecule in a reaction catalyzed by malate synthase, after the malate produced is oxidized to oxaloacetate and thus regenerating the intermediate (steps B-1 to B-5, Figure 1).
Malate synthase, GLcB, initially was characterized as an important enzyme of the glyoxylate shunt involved in carbon assimilation as energy source to bacilli [6].
Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis.