malarial pigment

ma·lar·i·al pig·'ment

a dark brown, granular pigment that rotates the plane of polarized light and has other properties similar to formalin pigment; occurs in parasitic infection, such as those caused by Plasmodium malariae, around brain capillaries, and in fixed macrophages of spleen, liver, bone marrow, and lymph nodes; composed of excess protein, an iron porphyrin, and hematin left over from the metabolism of hemoglobin by the malarial parasite within the red blood cell. See: malarial pigment stain.

malarial pigment

Black pigment in cerebral white matter composed of haematin and protein, which is a characteristic postmortem finding in Plasmodium falciparum malaria. Malarial brains are congested and oedematous, with indurated, flattened gyri and petechiae.
References in periodicals archive ?
C, Plasmodium spp metabolize heme groups into hemozoin within infected red blood cells (RBCs), which is the reason hemozoin should not be considered a "malarial pigment." D, Hemoglobin (Hb) is the principal component of RBCs.
Theories on malarial pigment formation and quinoline action.
Rare Findings in our Study: One of the rare findings in our study was phagocytosis of Malarial pigment by a monocyte, only 1 case (0.5%) was reported.
[beta]-Haematin forms as a crystalline cyclic dimer of oxidized heme and is complexed with protein and lipid products as malarial pigment or haemozoin.
falciparum, two cases of mixed infection and in one case the species could not be identified as the blood smear showed only malarial pigment. Among the patients with P.
DCs' activation is dynamically altered by pRBCs, partly because of deposition of the malarial pigment hemozoin within these cells and also other yet unknown parasite components which would down regulate the immune response (8).