malaria parasite


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Related to malaria parasite: Plasmodium falciparum

malaria parasite

the PROTOZOAN Plasmodium that causes malaria in man. It is transmitted by the Anopheles mosquito which takes in Plasmodium GAMETOCYTES when feeding on man. The gametocytes develop into male and female gametes in the mosquito stomach, and after fertilization the ZYGOTE bores through the stomach wall, encysts, and gives rise to thousands of sporozoites which then migrate to the salivary glands. The sporozoites are transferred to man at a subsequent blood meal during which anticoagulants are injected with the saliva to prevent blood clotting.

Sporozoites invade the human liver and give rise to merozoites that invade red blood corpuscles. Further production of merozoites occurs in the red blood corpuscle and their release into the blood stream gives rise to bouts of fever (‘malaria’). Gametocytes arise from merozoites which invade further red blood corpuscles, grow within them, and are withdrawn by the mosquito during feeding, to complete the life cycle.

References in periodicals archive ?
DHFR is the target of the antimalarial pyrimethamine -- a drug to which malaria parasites are increasingly developing resistance, particularly in Africa.
In addition, the team observed plasmepsin X in exonemes small vesicles (balloon-like structures) that help malaria parasites exit infected cells.
In addition, they also observed plasmepsin X in exonemes - small vesicles (balloon-like structures) that help malaria parasites exit infected cells.
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It came from a leading malaria parasite expert and so was difficult to dismiss lightly.
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Researchers have tested a handful of molecules that block NMT in malaria parasites living in human red blood cells and in mice.
It kills only the malaria parasite and does not affect the mosquito or humans, or even other bacteria" residing in the mosquito's gut, Jacobs-Lorena said in a phone interview.
Snug inside a human red blood cell, the malaria parasite hides from the immune system and fuels its growth by digesting hemoglobin, the cell's main protein.
THE malaria parasite can ensure it keeps a host body to itself by preventing further malarial infections, according to researchers.