malacoplakia


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malacoplakia

 [mal″ah-ko-pla´ke-ah]
a circumscribed area of softening on the membrane lining a hollow organ, as the ureter, urethra, or renal pelvis.
malacoplakia vesi´cae a flat yellow growth on the mucosa of the bladder and ureters, resulting from infection.

mal·a·co·pla·ki·a

, malakoplakia (mal'ă-kō-plā'kē-ă, mal'a-kō-plā'kē-a),
Rare lesion in the mucosa of the urinary bladder and other organs, more frequent in women, characterized by numerous mottled yellow and gray soft plaques and nodules that consist of numerous macrophages and calcospherites (Michaelis-Guttmann bodies) that may form around intracellular bacteria, usually Escherichia coli.
[malaco- + G. plax, plate, plaque]

mal·a·co·pla·ki·a

(mal'ă-kō-plā'kē-ă)
Rare lesion most commonly seen in the mucosa of the urinary bladder, characterized by mottled yellow and gray soft nodules that consist of macrophages and calcospherites (Michaelis-Guttmann bodies).
[malaco- + G. plax, plate, plaque]

malacoplakia

A form of persistent inflammation of the urinary bladder featuring soft, pale, elevated plaques composed of MACROPHAGES and LYMPHOCYTES. The condition most commonly affects middle-aged women.
References in periodicals archive ?
Malacoplakia is an unusual yet well-documented form of chronic xanthogranulomatous inflammation.
Malacoplakia in the urinary bladder should rarely cause diagnostic problems because most pathologists are aware of the condition in this location.
Many patients with malacoplakia have had associated bacterial infections, most often E coli infection.
With regard to the prognosis, malacoplakia is a heterogeneous disease with different patterns of aggressiveness.
Although malacoplakia was not initially considered in our patient, our intensive review of surgical specimens and careful inspection for MG bodies with various special stains ultimately led us to the correct diagnosis.
Combined occurrence of prostate carcinoma and malacoplakia. Pathol Oncol Res.
Case presentation of malacoplakia of the middle ear [in Spanish].
Malacoplakia of the tongue: a case report and review of the literature.
Fine needle aspiration cytology of malacoplakia of the thyroid: a case report.
Malacoplakia manifesting as a chronic inflammatory mass at the site of a nonhealing surgical wound.
Functional and morphological monocyte abnormalities in a patient with malacoplakia. Am J Med.