major tranquilizer

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a drug with a calming, soothing effect; currently it is usually used to mean an antianxiety agent (minor tranquilizer).
major tranquilizer former term for antipsychotic agent.
minor tranquilizer antianxiety agent.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

an·ti·psy·chot·ic a·gent

a functional category of neuroleptic drugs that are helpful in the treatment of psychosis and have a capacity to ameliorate thought disorders.
Farlex Partner Medical Dictionary © Farlex 2012

major tranquilizer

The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
References in periodicals archive ?
A study of 2,000 pharmacies in 1986 showed that 60.5% of prescriptions for nursing home residents over 65 years of age were for major tranquilizers and 17.
Yet another paper, published in The American Journal of Psychiatry in 1964, found that major tranquilizers can "produce an acute psychotic reaction in an individual not previously psychotic." A 1975 paper described a negative effect called akathisia, a drug-induced inability to sit still comfortably.
In contrast to the model that excludes ECT, this model no longer has major tranquilizers given at discharge as significant; instead, the model now includes the variable major antidepressants at admission, which adds 3.7 days to the LOS.
For demented patients, low-dose major tranquilizers can be helpful if a careful evaluation for other underlying problems, including depression, is first undertaken.