maintenance dose


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dose

 [dōs]
the quantity to be administered at one time, as a specified amount of medication or a given quantity of radiation.
absorbed dose that amount of energy from ionizing radiations absorbed per unit mass of matter, expressed in rads.
air dose the intensity of an x-ray or gamma-ray beam in air, expressed in roentgens.
booster dose an amount of immunogen (vaccine, toxoid, or other antigen preparation), usually smaller than the original amount, injected at an appropriate interval after primary immunization to sustain the immune response to that immunogen.
curative dose (CD) a dose that is sufficient to restore normal health. See also median curative dose.
divided dose fractionated dose.
effective dose (ED) that quantity of a drug that will produce the effects for which it is administered. See also median effective dose.
erythema dose that amount of radiation that, when applied to the skin, causes erythema (temporary reddening).
fatal dose lethal dose.
fractionated dose a fraction of the total dose prescribed, as of chemotherapy or radiation therapy, to be given at intervals, usually during a 24-hour period.
infective dose (ID) that amount of a pathogenic agent that will cause infection in susceptible subjects. See also median infective dose and tissue culture infective dose.
lethal dose (LD) that quantity of an agent that will or may be sufficient to cause death. See also median lethal dose and minimum lethal dose.
loading dose a dose of medication, often larger than subsequent doses, administered for the purpose of establishing a therapeutic level of the medication.
maintenance dose the amount of a medication administered to maintain a desired level of the medication in the blood.
maximum tolerated dose tolerance dose.
maximum permissible dose the largest amount of ionizing radiation that one may safely receive within a specified period according to recommended limits in current radiation protection guides. The specific amounts vary with age and circumstance.
median curative dose (CD50) a dose that abolishes symptoms in 50 per cent of test subjects.
median effective dose (ED50) a dose that produces the desired effect in 50 per cent of a population.
median infective dose (ID50) that amount of pathogenic microorganisms that will produce demonstrable infection in 50 per cent of the test subjects.
median lethal dose (LD50) the quantity of an agent that will kill 50 per cent of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50 per cent of individuals in a large group or population.
median tissue culture infective dose (TCID50) that amount of a pathogenic agent that will produce infection in 50 per cent of cell cultures inoculated.
minimum lethal dose
1. the amount of toxin that will just kill an experimental animal.
2. the smallest quantity of diphtheria toxin that will kill a guinea pig of 250-gm weight in 4 to 5 days when injected subcutaneously.
reference dose an estimate of the daily exposure to a substance for humans that is assumed to be without appreciable risk; it is calculated using the no observed adverse effect level and is more conservative than the older margin of safety.
skin dose (SD)
1. the air dose of radiation at the skin surface, comprising the primary radiation plus backscatter.
2. the absorbed dose in the skin.
threshold dose the minimum dose of ionizing radiation, a chemical, or a drug that will produce a detectable degree of any given effect.
threshold erythema dose (TED) the single skin dose that will produce, in 80 per cent of those tested, a faint but definite erythema within 30 days, and in the other 20 per cent, no visible reaction.
tissue culture infective dose (TCID) that amount of a pathogenic agent that will produce infection when inoculated on tissue cultures; used with a numeric qualifier.
tolerance dose the largest quantity of an agent that may be administered without harm. Called also maximum tolerated dose.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

main·te·nance drug ther·a·py

in chemotherapy, systematic dosage at a level that maintains protection against exacerbation.
Farlex Partner Medical Dictionary © Farlex 2012

maintenance dose

A dose of a drug administered after achieving stable levels in the body to maintain a therapeutic status quo.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

maintenance dose

Pharmacology A dose of a drug administered after achieving stable levels in the body, to maintain a therapeutic status quo. Cf Loading dose.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

main·te·nance drug ther·a·py

(māntĕ-năns drŭg thāră-pē)
In chemotherapy, systematic dosage at a level that maintains protection against exacerbation.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Canadian guidelines recommend oral intake of 50,000 IU of vitamin D2 or D3 weekly for eight weeks or 600 IU daily for two months followed by a maintenance dose of 1500-2000 IU/day.17
As demonstrated in Table 2, there was considerable variability in both the prescribed loading and maintenance doses, as well as in frequency of administration.
Caption: Figure 4: The maintenance dose of fentanyl when patients met the sequential criteria and the probability of developing delirium.
As the disease takes long period of time and improve slowly so observational study with maintenance dose of anti-psychotics beyond one year appear logical13-15.
If we would use recommended maintenance dose of IVIG (1g/kg), monthly dose would be 2040 g.
A maintenance dose below 7-10mg per day is the best.
For chronic joint conditions such as arthritis, tendonitis, and hip or elbow dysplasia, give the maintenance dose twice per day.
The maintenance dose is 10 to 20 mg orally every 4 to 6 hours, not to exceed 180 mg/day or 72 consecutive hours of treatment.
The corticosteroid dose of these patients is subsequently gradually decreased to a maintenance dose (daily prednisolone-equivalent dose is 10 mg or below) as clinical improvement is achieved.
The approved dosing regimen for adalimumab is a starting dose of 160 mg, followed by a second dose of 80 mg 2 weeks later and then a maintenance dose of 40 mg every other week.
The objective of this study was to see post extraction bleeding associated with long term maintenance dose of aspirin 75mg-150mg with out discontinuation.
With a secret heroin addiction, no doctor to prescribe her maintenance dose and a team of crooked policemen watching, Berlin has seven days to prove her innocence.

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