magnocellular neurosecretory cell


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magnocellular neurosecretory cell

A large, electrically excitable neuroendocrine neuron found in the supraoptic and paraventricular nuclei of the hypothalamus and in lesser numbers in accessory cell groups between these two nuclei, the largest one being the nucleus circularis which generates action potentials in response to afferent stimulation. Magnocellular neurosecretory cells produce oxytocin and/or vasopressin.
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References in periodicals archive ?
The observation that osmotic stimulation upregulated NOS as well as VP and OT mRNA expression in magnocellular neurosecretory cells (MNCs) of the SON was taken as evidence that NO could play a role as a neuromessenger involved in the control of neurohypophysial hormone secretion (16).
Direct and indirect mechanisms involved in the control of magnocellular neurosecretory cells (MNCs) firing frequency by nitric oxide (NO).