magnesium stearate


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mag·ne·si·um ste·a·rate

a compound of magnesium with variable proportions of stearic and palmitic acids; used in the preparation of tablets, as a lubricant, and as an ingredient in some baby powders.
References in periodicals archive ?
WiseGuyReports.com adds "Magnesium Stearate Market 2018 Global Analysis, Growth, Trends and Opportunities Research Report Forecasting to 2023" reports to its database
Stewart, "Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism?" International Journal of Pharmaceutics, vol.
At 40[degrees]C, under 75% of relative humidity, the excipients such as corn starch, croscarmellose sodium, magnesium stearate, polyvinyl alcohol, talc, PVP, lactose monohydrate, and PEG showed chemical incompatibility with AMLO and OLME, and because of it these excipients are not indicated for the preparation of formulations of AMLO and OLME.
Composition of naproxen sodium formulation (F1-F6) Formulation Naproxen sodium HPMC K100M Talc (1.5%) F1 375 75 mg - F2 375 150 mg - F3 375 225 mg - F4 375 37.5 mg 6.75 mg F5 375 37.5 mg 7.87 mg F6 375 37.5 mg 9.00 mg Formulation Magnesium stearate (1.5%) Talc (1%) F1 - 4.50 mg F2 - 5.25 mg F3 - 5.25 mg F4 6.75 mg - F5 7.87 mg - F6 9.00 mg - Formulation Magnesium stearate (1%) Ethyl cellulose F1 4.50 mg - F2 6.00 mg - F3 6.00 mg - F4 - 37.5 mg F5 - 37.5 mg F6 - 37.5 mg Table 2.
Magnesium stearate (MgSt) is a magnesium salt of stearic acid, which is widely used as a lubricant for tablets, capsules and powders in the pharmaceutical industry.
Ingredients (%) F1 F2 F3 F4 F5 F6 F7 Mosapride citrate 1 1 1 1 1 1 1 MCC 35 35 35 35 35 35 25 Mannitol 28.5 28.5 28.5 28.5 31 -- 36 Lactose 28.5 28.5 28.5 28.5 31 31 36 Pregelatinized starch -- -- -- -- -- 31 -- CCNa 5 -- -- -- -- -- -- CMS-Na -- 5 -- -- -- -- -- L-HPC -- -- 5 -- -- -- -- PVPP -- -- -- 5 -- -- -- Magnesium stearate 2 2 2 2 2 2 2 Table 2--Physical properties of tablets.
The ingredient is magnesium stearate. Magnesium stearate is a flow agent many supplement makers use in the capsules and tablets.
The lubricant magnesium stearate was also selected as its potential for over-lubrication is well recognized.
Tibolone (Symbiotica, Malaysia), lactose monohydrate (DMV Fonterra Excipients GmbH, Germany), starch 1500 (Colorcon, India), potato starch (Roquette, France), magnesium stearate (Ferro Corporation, USA).
Current products contain unwanted additives as sorbitol, croscarmellose, povidone, magnesium stearate and polisorbate 80.
Some excipient components (dicalcium phosphate, magnesium stearate and palmitate) reduce bioavailability.