There were multiple maculopapules
symmetrically distributed over the palms (a) and the soles (b), ranging from 2 to 10 cm in diameter.
(21) Dermal eruptions were the main manifestation, including maculopapules
, excoriations, and unusual vesicles and ulcers, etc.
Cutaneous manifestations of CSS are present in approximately 50% of patients and may be divided into three categories: erythematous maculopapules
, hemorrhagic lesions and cutaneous or subcutaneous nodules.
The cutaneous lesions may be classified as specific or non-specific depending on the presence or absence of granulomatous histology.2 Specific lesions include papules maculopapules
plaques nodules lupus pernio scar sarcoid ulcerative lesions hypopigmentation and many others.
Skin lesions may affect approximately 8% of cases, presenting typically as small nodules or erythematous or purpuric maculopapules
, but other morphological features of lesions are described.
Most rashes are characterized by scaly erythematous maculopapules
on the trunk, extremities, palms, and soles.
dermatitis has been described as a pruritic erythematous rash with maculopapules
with a central microvesicle (7).
The commonest form of cutaneous mastocytosis is urticaria pigmentosa.3 It develops in the first year of life in 84% of children in one study.4 The adult onset is between 20-40 years.5 The disease manifests as numerous reddish-brown, monomorphic maculopapules
or plaques, distributed symmetrically over the entire body except the face, head, palms and soles.6 To our knowledge this is the first case report of urticaria pigmentosa with involvement of palms and soles.
The elementary cutaneous element was an erythematous macule in 5 patients and maculopapules