The most common evolution of pigmentary change was following the generalized maculopapular rash
, which might be because of increased intraepidermal melanin dispersion/retention triggered by the virus.4,13 Variety of patterns like nose only, diffuse slate-gray facial, freckle like, generalized and periorbital were noted as has been seen in previous studies also.5,11-13 In addition, the pigmentation over nose which has been referred to as 'Chik sign' in a previous study11 was noted predominantly in males (Figure 1) while speckled and diffuse facial melanosis was noted predominantly in females (Figure 2 a and b).
With these new clinical, radiographic, and pathologic findings, there was concern for a CNS small vessel vasculitis possibly secondary to SLE given satisfaction of SLICC criteria which included low C4 and low CH50, high-titer double-stranded DNA, maculopapular rash
of the lower extremities, and bilateral papilledema and erythema resulting from cranial neuropathy of the optic nerves.
In this report, a case born to a mother with syphilis, and diagnosed via maculopapular rash
on the second day of life is described in order to emphasize the importance of early treatment in congenital syphilis.
Figure 1: Mild-to-moderate cutaneous adverse drug reactions Type of mild to moderate cutaneous adverse drug reactions Maculopapular rash
26.1% FDE 21.7% Erythematous rash 21.3% Acne 11% Urticaria 3.04% Others 3.32% Note: Table made from bar graph.
A previously healthy 27-year-old woman developed high-grade fever, maculopapular rash
with mild itching, weight loss, and polyarthralgia for 4 months.
Caption: FIGURE 4: Maculopapular rash
noted on admission on the patient's chest.
It presents as a maculopapular rash
involving the face and extremities, mucosal lesions, and condylomata lata.
Infection by ZIKV, can be asymptomatic in a large proportion of infected people (around 80%), and usually causes a mild clinical picture characterized by short-term, low-grade fever, followed by maculopapular rash
in the first or second day and intense pruritus.
He subsequently developed a maculopapular rash
secondary to a drug reaction/viral exanthema/infection associated hemophagocytosis/GVHD, which led on to liver cell failure and hence despite the aggressive treatment the child succumbed and died.
In addition to extreme fatigue, maculopapular rash
, headache and arthralgia, he developed symptoms of prostatitis with hematospermia upon his return to Colorado.
There was maculopapular rash
on upper chest and both lower legs, which was minimally itchy and not evanescent.
A maculopapular rash
usually appears 14-17 days after exposure and lasts 5-7 days.