However, single lesion frequency of reactive perforating collagenosis (RPC), blue nevus, atrophic skin lesions, cafe-au-lait macules, melasma, macular amyloidosis
, pigmented verruca vulgaris, lentigo maligna melanoma, dermatofibroma and pigmented basal cell carcinoma (BCC) was also seen, not mentioned in table.
due to amyloid deposition in the skin is characterized by clusters of small pigmented macules, which may coalesce to produce macular hyperpigmented areas commonly seen on the back and chest, usually as a result of chronic friction (16).
Among the 11 cases of macular amyloidosis, 8 had predominant upper limb involvement (left sided in 6) and posterior trunk alone affected in 3 cases of macular amyloidosis.
The scrub use was more prevalent among lichen amyloidosis patients (85%), followed by biphasic amyloidosis (71.42%) and macular amyloidosis (63.63%).
and lichen amyloidosis are named as biphasic amyloidosis when they are concurrently seen in a patient.
A RET mutation in exon 13 was confirmed in the latter; thus, it is unclear whether this patient had an unusual presentation of MEN2B or an overlap of MEN2A/2B, as the patient also had macular amyloidosis
. Multiple cutaneous neuromas without systemic abnormalities have been reported in 5 patients (2,11,13,14,15).
with localized amyloidosis of upper air passages.
Patients who responded well to the drug included those with underlying diagnoses of liver cirrhosis, chronic renal failure, diabetes mellitus, cutaneous lymphoma, xerosis cutis, bullous pemphigoid, psoriasis, macular amyloidosis
, and prurigo nodularis (J.
On histopathological examination of 85 cases, 11 were classical Lichen planus and 09 were its morphological variants (Figure 2); 5 cases of Psoriasis, 5 cases of Prurigo nodularis, 4 cases of Morphea (Figure 3), 4 cases of Lichen simplex chronicus, 3 cases of Lichen striatus, 3 cases of Verruca plana, 3 cases of Becker nevus, 2 cases of Pemphigus foliaceus, 2 cases of Linear epidermal nevus (Figure 4), 2 cases of Macular amyloidosis
, 2 cases of Lentigo simplex, 2 cases of LSEA and one case each of other lesions as shown in Table 1.
Other associated disorders are calciphylaxis, xerosis, xanthelasma, lipodystrophy, macular amyloidosis
and alopecia.3 Commonly seen viral infections include herpes zoster and viral warts.4
INTRODUCTION: Macular amyloidosis
(MA) is a common variant of primary localized cutaneous amyloidosis with a characteristic female preponderance [1-7] and the age of onset ranging between 21 and 50 years.
There are many conditions which need to be considered before making a diagnosis of acquired macular hyperpigmentation like erythema dyschromicum perstans, lichen planus pigmentosus, macular amyloidosis
, tar and frictional melanosis, post-inflammatory hyperpigmentation, Berloque dermatitis, Riehl's melanosis and drugs and chemicals.